1-((2-Chlorophenyl)sulfonyl)piperidine-3-carboxylic acid CAS 630049-60-4
| CAS No. | 630049-60-4 |
| Molecular Formula | C12H14ClNO4S |
| Molecular Weight | 303.76 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
1-((2-Chlorophenyl)sulfonyl)piperidine-3-carboxylic acid (CAS 630049-60-4), molecular formula C12H14ClNO4S and molecular weight 303.76 g/mol, is a CATO reference standard with documented purity and traceability.
1-((2-Chlorophenyl)sulfonyl)piperidine-3-carboxylic acid (C12H14ClNO4S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO4S |
| Molecular Weight | 303.76 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 1-[(2-Chlorophenyl)sulfonyl]piperidine-2-carboxylic acid (CAS 1008704-40-2)
- 3-(4-Chlorophenyl)-2-(phenylsulfonyl)acrylonitrile (CAS 129200-98-2)
- 1-((2-Chlorophenyl)sulfonyl)piperidine-4-carboxylic acid (CAS 630049-59-1)
- 1-((4-Chlorophenyl)sulfonyl)piperidine-2-carboxylic acid (CAS 379223-45-7)
- 1-[(4-chlorophenyl)sulfonyl]piperidine-3-carboxylic acid (CAS 321970-56-3)
- 1-[(4-Chlorophenyl)sulfonyl]piperidine-4-carboxylic acid (CAS 314744-43-9)
- 2-((2-Chlorophenyl)sulfonyl)-1-morpholinoethan-1-one (CAS 339097-93-7)
- 3-(4-Chlorophenyl)-2-(phenylsulfonyl)acrylonitrile (CAS 50709-88-1)
Recommended Standards
- (4-(Azetidin-1-ylmethyl)phenyl)(2-chloro-4-fluorophenyl)methanone (CAS 898756-89-3)
- (3-(Azetidin-1-ylmethyl)phenyl)(4-chloro-3-fluorophenyl)methanone (CAS 898771-83-0)
- (3-(Azetidin-1-ylmethyl)phenyl)(3-chloro-5-fluorophenyl)methanone (CAS 898772-01-5)
- 1-(2-Chloro-6-fluorobenzyl)-1,3,4,5-tetrahydro-2H-benzo[b]azepin-2-one (CAS 303987-97-5)
- 2-(4-Chlorophenyl)-3-methyl-N-(thiazol-2-yl)butanamide (CAS 300851-67-6)
- 5-(3-Methylbutylthio)-1,3,4-thiadiazol-2-thiol (CAS 344926-02-9)
- 5-Nitro-2-(pyrimidin-2-ylthio)benzaldehyde (CAS 591747-15-8)
- 1-Bromo-3-(cyclopropylmethyl)benzene (CAS 931430-39-6)
- 2-Hydrazino-5,7-dimethyl-1,3-benzothiazole (CAS 872696-08-7)
- 5-Methyl-1-(2,2,2-trifluoroethyl)-1h-pyrazole-3-carboxylic acid (CAS 1006486-45-8)
- 3-isopropylthiomorpholine (CAS 29442-20-4)
- 4-Chloro-2-(3,5-dichlorophenyl)-5-(1-methylhydrazino)-2,3-dihydropyridazin-3-one (CAS 175135-84-9)
- N-{3-(Dimethylamino)-1-[(4-methoxyphenyl)sulfonyl]-1H-1,2,4-triazol-5-yl}-N,N-dimethylamine (CAS 478032-04-1)
- Fragment-[9-31]-Semaglutide (CAS CATO-C4X-2226181)
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