2-(1,2,3,4-Tetrahydroisoquinolin-3-yl)acetonitrile CAS 63006-86-0
| CAS No. | 63006-86-0 |
| Molecular Formula | C11H12N2 |
| Molecular Weight | 172.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(1,2,3,4-Tetrahydroisoquinolin-3-yl)acetonitrile (CAS 63006-86-0), molecular formula C11H12N2 and molecular weight 172.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-(1,2,3,4-Tetrahydroisoquinolin-3-yl)acetonitrile (C11H12N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H12N2 |
| Molecular Weight | 172.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Tetrahydroisoquinolin Standards
- 2-(1,2,3,4-tetrahydroisoquinolin-2-yl)acetonitrile (CAS 91349-97-2)
- 3-Ethyl-1,2,3,4-tetrahydroisoquinolin-1-one (CAS 112794-32-8)
- 1-(1,2,3,4-Tetrahydroisoquinolin-2-yl)ethan-1-one (CAS 14028-67-2)
- 1-(1,2,3,4-Tetrahydroisoquinolin-8-yl)ethan-1-one (CAS 1784449-70-2)
- 1-(1,2,3,4-Tetrahydroisoquinolin-6-yl)ethan-1-one (CAS 949922-27-4)
- 1-(1,2,3,4-Tetrahydroisoquinolin-7-yl)ethan-1-one (CAS 82771-59-3)
- (2-Methyl-1,2,3,4-tetrahydroisoquinolin-3-yl)methanamine (CAS 718589-10-7)
- 2-ethyl-1,2,3,4-tetrahydroisoquinolin-4-amine (CAS 61695-04-3)
Recommended Standards
- 2-(1,2,3,4-Tetrahydroquinolin-1-yl)acetonitrile (CAS 66487-31-8)
- 2-((5-Amino-1,3,4-thiadiazol-2-yl)thio)acetonitrile (CAS 72836-34-1)
- 2-(1H-Indol-3-yl)cyclopropanamine (CAS 91349-95-0)
- 1-Phenylpyrrolidine-2-carbonitrile (CAS 893086-81-2)
- 6-(Methylamino)-2-phenylpyrimidin-4(3H)-one (CAS 31937-01-6)
- 2-(Adamantan-1-yl)-1-morpholinoethan-1-one (CAS 259196-32-2)
- 4,4-Dimethyl-5-nitropentan-2-one (CAS 35223-73-5)
- ((2R,3R,4S,5R)-3-(Benzoyloxy)-4-fluoro-5-(5-fluoro-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl benzoate (CAS 952651-49-9)
- n1-Isopropyl-6-methylbenzene-1,2-diamine (CAS 180207-83-4)
- 2-Cyano-N-(4-(methylsulfonyl)phenyl)acetamide (CAS 1016833-99-0)
- 5-Methylbenzo[d]thiazole-2-thiol (CAS 21303-50-4)
- (R)-1-(tert-Butoxycarbonyl)-2-(4-iodobenzyl)-pyrrolidine-2-carboxylic acid (CAS 959576-49-9)
- 4-(2-Amino-1-phenylpropoxy)oxane hydrochloride (CAS 1423031-70-2)
- Insulin Glargine Metabolite M2 (CAS CATO-CPTD788867)
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