5-Chloro-4,6-bis(methylthio)pyrimidine CAS 6303-52-2

Purity 97%+In StockPharmaceutical Standards
CAS No.6303-52-2
Molecular FormulaC10H14ClO3PS
Molecular Weight280.71 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-4,6-bis(methylthio)pyrimidine CAS 6303-52-2 chemical structure

Description

The occurrence of 5-Chloro-4,6-bis(methylthio)pyrimidine is closely related to a sulfone group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 5-Chloro-4,6-bis(methylthio)pyrimidine (CAS 6303-52-2), a certified reference material (molecular formula C10H14ClO3PS, MW 280.71 g/mol) for analytical method development and quality control.

The molecular framework of 5-Chloro-4,6-bis(methylthio)pyrimidine (C10H14ClO3PS) is characterized by a sulfone group, a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Chloro-4,6-bis(methylthio)pyrimidine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC10H14ClO3PS
Molecular Weight280.71 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1958
Halogen ContentCl-containing
Sulfur Atoms1

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