5-(Thiophen-2-ylthio)thiophene-2-sulfonamide CAS 63033-64-7
| CAS No. | 63033-64-7 |
| Molecular Formula | C8H7NO2S4 |
| Molecular Weight | 277.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-(Thiophen-2-ylthio)thiophene-2-sulfonamide (CAS 63033-64-7), molecular formula C8H7NO2S4 and molecular weight 277.41 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, 5-(Thiophen-2-ylthio)thiophene-2-sulfonamide is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 277.41 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H7NO2S4 |
| Molecular Weight | 277.41 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 4 |
Related Thiophen Standards
- 4-(Thiophen-2-yl)-4,6,7,8-tetrahydro-1H-5,8-ethanopyrido[3,2-d]pyrimidine-2(3H)-thione (CAS 82955-23-5)
- 2-(((Thiophen-2-ylmethyl)amino)methyl)thieno[3,2-d]pyrimidin-4(3h)-one (CAS 849125-86-6)
- N-(2-(Thiophen-2-yl)ethyl)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-2-carboxamide (CAS 1448077-35-7)
- 3-((Thiophen-2-ylmethyl)carbamoyl)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid (CAS 331416-18-3)
- 2-(4-Oxo-2-(thiophen-2-yl)-6,7-dihydropyrazolo[1,5-a]pyrazin-5(4H)-yl)acetic acid (CAS 1707735-52-1)
- 4-Oxo-5-(thiophen-2-ylmethyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid (CAS 924645-68-1)
- 4-Oxo-5-(thiophen-2-ylmethyl)-6,7-dihydropyrazolo[1,5-a]pyrazine-3-carboxylic acid (CAS 685106-60-9)
- 1-Methyl-5-(thiophen-3-yl)-5,8-dihydropyrimido[4,5-d]pyrimidine-2,4,7(1H,3H,6H)-trione (CAS 1170146-42-5)
Recommended Standards
- 4-Allyl-5-(4,5,6,7-tetrahydro-1-benzothien-3-yl)-4H-1,2,4-triazole-3-thiol (CAS 522597-46-2)
- N,N-dimethyl-4-(((3-morpholinopropyl)amino)methyl)aniline (CAS 436096-94-5)
- (5E)-5-(4-tert-Butylbenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one 312607-49-1 9879AD C14H15NOS2 (CAS 312607-49-1)
- 1-[2-(Prop-2-en-1-ylsulfanyl)thieno[3,2-d]pyrimidin-4-yl]pyrrolidine (CAS 339019-35-1)
- 2,5-Dimethyl-4-(4-methylpiperazinomethyl) benzophenone (CAS 898783-73-8)
- 4-(aminomethyl)-1,2-dihydroquinolin-2-one hydrochloride (CAS 132973-42-3)
- Tert-butyl (2-(((tert-butyldimethylsilyl)oxy)methyl)furo[3,2-b]pyridin-6-yl)carbamate (CAS 1171920-60-7)
- 2-Methyl-3-(propyldisulfanyl)furan (CAS 61197-09-9)
- 2-Methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxylic acid (CAS 1386981-01-6)
- 14378-39-3 (CAS 14378-39-3)
- N-(5-Cyclopropoxy-6-nitropyridin-3-yl)methanesulfonamide (CAS 1243440-60-9)
- 3,6-Diiodo-9-(oxiran-2-ylmethyl)-9H-carbazole (CAS 139651-59-5)
- Piribedil Impurity 4 (CAS CATO-C4X-28134)
- Nonapeptide-1 (CAS 158563-45-2)
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