1-Chloro-7-fluoro-6-methoxyisoquinoline CAS 630422-99-0
| CAS No. | 630422-99-0 |
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-Chloro-7-fluoro-6-methoxyisoquinoline is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-Chloro-7-fluoro-6-methoxyisoquinoline (CAS 630422-99-0), molecular formula C10H7ClFNO and molecular weight 211.62 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Chloro-7-fluoro-6-methoxyisoquinoline (C10H7ClFNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-Chloro-7-fluoro-6-methoxyisoquinoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7ClFNO |
| Molecular Weight | 211.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 2-(4-Chloro-1h-pyrazol-1-yl)-5-fluoroaniline (CAS 1006468-20-7)
- 4-(4-Chloro-1h-pyrazol-1-yl)-3-fluoroaniline (CAS 1006960-83-3)
- (2-Chloro-6-fluoroquinolin-3-yl)methanol (CAS 1017403-67-6)
- (2-Chloro-7-fluoroquinolin-3-yl)methanol (CAS 1017429-31-0)
- 3-Chloro-4-(4-fluorobenzyl)-4h-1,2,4-triazole (CAS 1019033-05-6)
- 4-(2-Chloro-4-fluorophenyl)-1,2-dihydro-3h-pyrazol-3-imine (CAS 1048971-88-5)
- 4-(4-Chloro-2-fluorophenyl)-1H-pyrazol-5-amine (CAS 1048971-89-6)
- 2-Chloro-6-fluoro-8-methoxyquinoline (CAS 1086398-43-7)
Recommended Standards
- 1-Chloro-7-fluoro-4-methoxyisoquinoline (CAS 630423-46-0)
- 2-(2-Chloro-6-fluorophenyl)-3-oxobutanenitrile (CAS 93839-17-9)
- 1-Chloro-6-fluoro-7-methoxyisoquinoline (CAS 905994-28-7)
- 2-(chloromethyl)-5-(4-fluorophenyl)-1,3-oxazole (CAS 64640-14-8)
- Ethyl 1-(piperidin-4-yl)-1H-pyrazole-4-carboxylate (CAS 782493-96-3)
- (Bicyclo[2.2.1]hepta-2,5-diene)[1,4-bis(diphenylphosphino)butane]rhodium(I) tetrafluoroborate 2756AC 82499-43-2 C35H36BF4P2Rh (CAS 82499-43-2)
- 2-(Furan-2-yl)-1,3-dioxan-5-ol (CAS 1708-43-6)
- N-methyl-1-(piperidin-2-yl)-N-((tetrahydro-2H-pyran-4-yl)methyl)methanamine dihydrochloride (CAS 1219963-99-1)
- 2-Ethoxy-2,3-dimethylpentan-1-amine (CAS 1496312-01-6)
- Pterosin G (CAS 35964-50-2)
- (4-Bromo-2-(difluoromethyl)-6-methylpyridin-3-yl)methanol (CAS 1804429-27-3)
- N-Hydroxy Mexiletine (CAS 55304-17-1)
- 1-chloro-4,7-difluoro-2,3-dihydro-1H-indene (CAS 1188233-02-4)
- Liraglutide Sodium Salt (CAS 204656-20-2（free base）)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com