3-Methyl-2-(1,2,2,2-tetrafluoroethyl)quinazolin-4(3H)-one CAS 63077-35-0
| CAS No. | 63077-35-0 |
| Molecular Formula | C11H8F4N2O |
| Molecular Weight | 260.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 3-Methyl-2-(1,2,2,2-tetrafluoroethyl)quinazolin-4(3H)-one (CAS 63077-35-0), a certified reference material (molecular formula C11H8F4N2O, MW 260.19 g/mol) for analytical method development and quality control.
The molecular framework of 3-Methyl-2-(1,2,2,2-tetrafluoroethyl)quinazolin-4(3H)-one (C11H8F4N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8F4N2O |
| Molecular Weight | 260.19 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Methyl Standards
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Recommended Standards
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Why CATO?
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