4-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-amine CAS 63156-73-0
| CAS No. | 63156-73-0 |
| Molecular Formula | C10H8F3N3 |
| Molecular Weight | 227.19 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-amine (CAS 63156-73-0), molecular formula C10H8F3N3 and molecular weight 227.19 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 4-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-amine (C10H8F3N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 227.19 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 4-Phenyl-3-(trifluoromethyl)-1H-pyrazol-5-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8F3N3 |
| Molecular Weight | 227.19 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Phenyl Standards
- 7-(Trifluoromethyl)quinoline-3,4-diamine (CAS 110643-85-1)
- 1-(3-(Trifluoromethyl)benzyl)-1H-1,2,4-triazole (CAS 115201-44-0)
- 3-[5-(trifluoromethyl)-1h-pyrazol-1-yl]aniline (CAS 1152530-85-2)
- 1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-4-amine (CAS 1153040-21-1)
- 1-(2-(Trifluoromethyl)phenyl)-1h-pyrazol-3-amine (CAS 1248322-84-0)
- 1-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-amine (CAS 1251264-73-9)
- 3-[4-(trifluoromethyl)-1h-pyrazol-1-yl]aniline (CAS 1306605-68-4)
- 1-(2-(Trifluoromethyl)phenyl)-1h-pyrazol-5-amine (CAS 1349717-35-6)
Recommended Standards
- 4-Hydrazinyl-8-(trifluoromethyl)quinoline (CAS 57369-92-3)
- 5-(3-Trifluoromethyl-phenyl)-2H-pyrazol-3-ylamine (CAS 209224-91-9)
- 4-Hydrazinyl-7-(trifluoromethyl)quinoline (CAS 49612-01-3)
- 5-Nitrobenzo[b]thiophen-3(2H)-one 1,1-Dioxide (CAS 343348-19-6)
- 6-Mercapto-5-(3-methoxy-propyl)-1,2,3,5-tetrahydro-8-thia-5,7-diaza-cyclopenta[a]inden-4-one (CAS 565174-25-6)
- 2K-322S 3-{5,6-dichloro-1-[(4-chlorophenyl)methyl]-1H-1,3-benzodiazol-2-yl}-1,2-dihydropyridin-2-one 338774-07-5 (CAS 338774-07-5)
- Serpent Peptide 2AcOH (CAS 823202-99-9(free base))
- Voriconazole USP Related Compound A (CAS 137330-52-0)
- 5-[(Z)-2-(2,3-Dimethylphenyl)diazen-1-yl]-4-(4-methylphenyl)pyrimidin-2-amine (CAS 338414-18-9)
- Methyl 3-fluoro-2-(trifluoromethyl)benzoate (CAS 918873-52-6)
- (R)-Benzyl (1-(2-chloroacetyl)pyrrolidin-3-yl)(ethyl)carbamate (CAS 1353994-92-9)
- 2-Amino-5-(3-methoxyphenyl)-5-[(3,4,5-trimethoxyphenyl)methyl]-4,5-dihydro-1H-imidazol-4-one (CAS 1354924-56-3)
- 2-(4-Butylphenyl)-6-chloroquinoline-4-carbonyl chloride (CAS 1160263-19-3)
- Semaglutide impurity 202 (CAS CATO-C4X-2226202)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com