6-Chloro-N4-ethylpyrimidine-2,4-diamine CAS 6316-09-2
| CAS No. | 6316-09-2 |
| Molecular Formula | C6H9ClN4 |
| Molecular Weight | 172.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 6-Chloro-N4-ethylpyrimidine-2,4-diamine (C6H9ClN4) is characterized by a nitrile group, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
6-Chloro-N4-ethylpyrimidine-2,4-diamine (CAS 6316-09-2), molecular formula C6H9ClN4 and molecular weight 172.62 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C6H9ClN4 |
| Molecular Weight | 172.62 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 6-Chloro-N4,N4-dimethylpyrimidine-2,4-diamine (CAS 1007-11-0)
- 6-Chloro-n4-ethylpyridazine-3,4-diamine (CAS 1025509-63-0)
- 6-Chloro-N2,N2-dimethylpyrimidine-2,4-diamine (CAS 1075-39-4)
- 5-Chloro-4-hydrazinyl-2,6-dimethylpyrimidine (CAS 1242652-34-1)
- 2-Chloro-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[1,5-a][1,4]diazepine (CAS 1260663-49-7)
- 3-Chloro-6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a][1,4]diazepine (CAS 1260667-13-7)
- 6-Chloro-4-N,4-N-dimethylpyrimidine-4,5-diamine (CAS 130623-81-3)
- 4-Chloro-6-isopropyl-1,3,5-triazin-2-amine (CAS 188624-04-6)
Recommended Standards
- 6-Chloro-N2-ethylpyrimidine-2,4-diamine (CAS 70958-42-8)
- 6-Chloro-N4-ethylpyrimidine-4,5-diamine (CAS 98140-03-5)
- 6-Chloro-2-ethylpyrimidine-4,5-diamine (CAS 6237-97-4)
- 6-Chloro-N5-ethylpyrimidine-4,5-diamine (CAS 885500-43-6)
- N-(4,6-Diphenylpyrimidin-2-yl)acetamide (CAS 58413-41-5)
- 2-Chloro-5-((4-methyl-1H-pyrazol-1-yl)methyl)pyridine (CAS 1183842-17-2)
- (S)-4-Methyl-2-(methylsulfonamido)pentanoic acid (CAS 36724-95-5)
- 5-Methyl-1-propyl-1H-pyrazole-4-carbaldehyde (CAS 890652-02-5)
- (±)-7-Methyl-d3-nonanoic Acid (CAS 41653-89-8)
- Ethyl 8-methoxy-6-methyl-4-thioxo-1,4-dihydroquinoline-3-carboxylate (CAS 1315352-11-4)
- 5-Acetyl-6-methyl-2-[(2-methylpropyl)sulfanyl]pyridine-3-carbonitrile (CAS 303146-30-7)
- Pyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione (CAS 258282-54-1)
- Methyl 2-((4S,5R,6S)-5,6-dihydroxy-5,6-dihydro-4H-cyclopenta[c]furan-4-yl)acetate (CAS 752225-58-4)
- Semaglutide Impurity 11 (CAS CATO-C4X-222611)
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