Piperazine Impurity 3 CAS 63167-05-5
| CAS No. | 63167-05-5 |
| Molecular Formula | C15H17NS |
| Molecular Weight | 243.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Piperazine Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Piperazine Impurity 3 (CAS 63167-05-5), a pharmacopoeial impurity reference standard (molecular formula C15H17NS, MW 243.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, Piperazine Impurity 3 is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 243.37 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C15H17NS |
| Molecular Weight | 243.37 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Piperazine Standards
- 1-(Piperazine-1-carbonyl)piperidine-4-carboxylic acid (CAS 1171309-80-0)
- 1-(Piperazine-1-carbonyl)piperidine-3-carboxylic acid (CAS 1172692-53-3)
- Piperazine Impurity 38 (CAS 64728-49-0)
- N-(3-(piperazine-1-carbonyl)phenyl)acetamide (CAS 1181625-75-1)
- Piperazine Impurity 33 (CAS 2639426-95-0)
- 1,1'-(Piperazine-1,4-diyl)bis(2-chloroethanone) (CAS 1703-23-7)
- 4-Benzyl-piperazine-1-carbonylchloride (CAS 63763-66-6)
- Methyl 3-(piperazine-1-carbonyl)benzoate (CAS 1338652-13-3)
Recommended Standards
- (1-Phenyl-but-3-enyl)thiophen-2-ylmethyl-amine 1-phenyl-N-(thiophen-2-ylmethyl)but-3-en-1-amine 436088-65-2 (CAS 436088-65-2)
- (2-(Dimethyl(pyridin-3-yl)silyl)phenyl)methanol (CAS 1217863-70-1)
- Tert-butyl 7-thia-2-azaspiro[3.5]nonane-2-carboxylate (CAS 2892449-77-1)
- 2-Bromo-2,3,3,3-tetrafluoropropionyl chloride (CAS 6066-45-1)
- Valsartan EP Impurity B (CAS 137863-20-8)
- Sitagliptin Impurity 150 (CAS 945261-47-2)
- Bempedoic Acid Impurity 25 (CAS 2511500-14-2)
- (2R,4r,5S)-5-aminospiro[3.3]Heptane-2-carboxylic acid (CAS 1682749-10-5)
- 3-(Isopropoxymethyl)pyrrolidine (CAS 1083368-75-5)
- (R)-1-(2-chloro-6-methoxyphenyl)ethan-1-amine (CAS 1270058-14-4)
- 4-Methylenepiperidine hydrobromide (CAS 3522-98-3)
- Tofacitinib Impurity 98 (CAS CATO-C4X-107998)
- tert-butyl 2-(2-((2,4-dichloropyrimidin-5-yl)methoxy)ethyl)piperidine-1-carboxylate (CAS 1420983-38-5)
- Dulaglutide (CAS 923950-08-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com