4-Nitroso-3,4-dihydro-2H-benzo[b][1,4]oxazine CAS 63169-10-8
| CAS No. | 63169-10-8 |
| Molecular Formula | C8H8N2O2 |
| Molecular Weight | 164.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 164.16 g/mol gives 4-Nitroso-3,4-dihydro-2H-benzo[b][1,4]oxazine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 4-Nitroso-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 63169-10-8), a certified reference material (molecular formula C8H8N2O2, MW 164.16 g/mol) for analytical method development and quality control.
The molecular framework of 4-Nitroso-3,4-dihydro-2H-benzo[b][1,4]oxazine (C8H8N2O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Nitroso-3,4-dihydro-2H-benzo[b][1,4]oxazine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8N2O2 |
| Molecular Weight | 164.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 4-Nitroisoindoline (CAS 748735-45-7)
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- Tert-butyl (5-cyanotetrahydro-2H-pyran-3-yl)carbamate (CAS 2113502-21-7)
- Valcor (CAS 59182-63-7)
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- (5-methyl-2-pyridyl)hydrazine;hydrochloride (CAS 1375477-15-8)
- S-{[(4-Chlorophenyl)sulfanyl](difluoro)methyl} O-ethyl carbonodithioate (CAS 1563062-31-6)
- 4-[(9-Anthracenylmethylene)amino]-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one (CAS 303019-69-4)
- (2-Chloro-6,7-dimethoxyquinolin-3-yl)methanol (CAS 92172-84-4)
- Tenofovir Alafenamide Impurity 18 (CAS 379270-35-6)
- 2-((3-(Trifluoromethyl)benzyl)sulfonyl)ethanethioamide (CAS 175276-83-2)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
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