(5E)-5-(3-Ethoxy-4-hydroxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one CAS 6322-57-2
| CAS No. | 6322-57-2 |
| Molecular Formula | C12H11NO3S2 |
| Molecular Weight | 281.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(5E)-5-(3-Ethoxy-4-hydroxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 6322-57-2) is a high-purity analytical reference standard with the molecular formula C12H11NO3S2 and a molecular weight of 281.35 g/mol.
The molecular framework of (5E)-5-(3-Ethoxy-4-hydroxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (C12H11NO3S2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (5E)-5-(3-Ethoxy-4-hydroxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11NO3S2 |
| Molecular Weight | 281.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related E Standards
- 2-Butyl-4-ethoxy-5-morpholinopyridazin-3(2H)-one (CAS 51659-93-9)
- (5E)-5-(3-Ethoxy-2-hydroxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one 4744AF 99988-45-1 C12H11NO3S2 (CAS 99988-45-1)
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Recommended Standards
- (5E)-5-(3,4-Dimethoxybenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one (CAS 6326-74-5)
- (E)-5-(3-hydroxy-4-methoxybenzylidene)-3-methyl-2-thioxothiazolidin-4-one (CAS 331261-30-4)
- (4-tert-Butoxy-pyrimidin-2-ylmethyl)-carbamic acid tert-butyl ester (CAS 2365420-00-2)
- (R)-2-([2,2'-Bipyridin]-6-yl)-4-(tert-butyl)-4,5-dihydrooxazole (CAS 2757082-47-4)
- N-(4-Hydroxyphenyl)-4-methoxy-N-methylbenzene-1-sulfonamide (CAS 124772-07-2)
- n-((2-Ethylthiazol-4-yl)methyl)-1-(1h-pyrazol-1-yl)propan-2-amine (CAS 1311886-35-7)
- 3',4'-Dimethyl-[1,1'-biphenyl]-3-amine hydrochloride (CAS 1189877-31-3)
- 4-(Difluoromethoxy)cyclohexanol (CAS 1565472-22-1)
- 5-Amino-1-benzyl-3-methyl-1H-pyrazole-4-carbonitrile (CAS 168465-06-3)
- Potassium Dodecanoate-2,2-d2 (CAS 82867-25-2)
- 4'-Fluoro-2'-methyl-[1,1'-biphenyl]-3-thiol (CAS 1443325-62-9)
- tert-Butyl N-[2-(2-methoxyphenyl)propan-2-yl]carbamate (CAS 1338222-73-3)
- N-(Piperidin-4-yl)cyclopropanesulfonamide hydrochloride (CAS 1403952-83-9)
- Semaglutide impurity 59 (CAS CATO-C4X-222659)
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