Methyl 3-amino-4-chlorothiophene-2-carboxylate CAS 632356-41-3

Purity 97%+In StockPharmaceutical Standards
CAS No.632356-41-3
Molecular FormulaC6H6ClNO2S
Molecular Weight191.64 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

Methyl 3-amino-4-chlorothiophene-2-carboxylate CAS 632356-41-3 chemical structure

Description

The occurrence of Methyl 3-amino-4-chlorothiophene-2-carboxylate is closely related to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

Methyl 3-amino-4-chlorothiophene-2-carboxylate (CAS 632356-41-3), molecular formula C6H6ClNO2S and molecular weight 191.64 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of Methyl 3-amino-4-chlorothiophene-2-carboxylate (C6H6ClNO2S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H6ClNO2S
Molecular Weight191.64 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentCl-containing
Nitrogen Atoms1
Sulfur Atoms1

Related Methyl Standards

Recommended Standards

Why CATO?