2-(2-Hydroxyphenoxy)acetic acid CAS 6324-11-4
| CAS No. | 6324-11-4 |
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(2-Hydroxyphenoxy)acetic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-(2-Hydroxyphenoxy)acetic acid (CAS 6324-11-4) is a high-purity analytical reference standard with the molecular formula C8H8O4 and a molecular weight of 168.15 g/mol.
The molecular framework of 2-(2-Hydroxyphenoxy)acetic acid (C8H8O4) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(2-Hydroxyphenoxy)acetic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H8O4 |
| Molecular Weight | 168.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
Related Hydroxyphenoxy Standards
- 2-(3-Hydroxyphenoxy)acetic acid (CAS 1878-83-7)
- 2-(3-hydroxyphenoxy)acetamide (CAS 1152538-30-1)
- 2-(2-Hydroxyphenoxy)acetamide (CAS 34919-87-4)
- 2-(4-hydroxyphenoxy)acetamide (CAS 22446-14-6)
- 3-(2-Hydroxyphenoxy)-2-butanone (CAS 91061-42-6)
- 2-(3-Hydroxyphenoxy)propanamide (CAS 1152572-45-6)
- 2-(4-hydroxyphenoxy)propanamide (CAS 127437-43-8)
- 2-(3-Hydroxyphenoxy)-n-methylacetamide (CAS 34918-51-9)
Recommended Standards
- 2-(2-Amino-2-oxoethyl)-1H-pyrrole-3-carboxylic acid (CAS 67464-87-3)
- 2-(3-Amino-2-oxopyridin-1(2h)-yl)acetic acid (CAS 300582-90-5)
- 2-(2,6-Dihydroxyphenyl)acetic acid (CAS 64700-73-8)
- 2-(3-Methyl-6-oxo-1,6-dihydropyridazin-1-yl)acetic acid (CAS 412018-60-1)
- 3,4-Dimethyl-4H-pyrido[2,3-e][1,2,4]thiadiazine 1,1-dioxide (CAS 73077-68-6)
- 6-Methyl-3-(thiophen-2-yl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1708437-09-5)
- 3-(Naphthalen-1-ylmethyl)-2,3-dihydro-1,3-thiazol-2-imine hydrochloride (CAS 1172880-63-5)
- Tirofiban Impurity 72 (CAS CATO-C4X-125472)
- Eltrombopag Impurity 65 (CAS CATO-C4X-119865)
- Azelastine Impurity 47 (CAS CATO-C4X-139647)
- (R)-tert-Butyl (3-(1-aminoethyl)-4-fluorophenyl)carbamate (CAS 2227768-74-1)
- [Ir(cod)(acac)] (CAS 12154-84-6)
- (4-chlorophenyl)({8-methyl-8-azabicyclo[3.2.1]octan-3-yl})methanamine (CAS 1708293-19-9)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
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