2-(4-Chlorophenyl)propionyl chloride CAS 63327-24-2
| CAS No. | 63327-24-2 |
| Molecular Formula | C9H8Cl2O |
| Molecular Weight | 203.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(4-Chlorophenyl)propionyl chloride (CAS 63327-24-2) is a high-purity analytical reference standard with the molecular formula C9H8Cl2O and a molecular weight of 203.07 g/mol.
2-(4-Chlorophenyl)propionyl chloride (C9H8Cl2O) contains a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(4-Chlorophenyl)propionyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H8Cl2O |
| Molecular Weight | 203.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
Related Chlorophenyl Standards
- 3-(3-Chlorophenyl)propanoyl chloride (CAS 40478-50-0)
- o-Chlorophenyl thioacetate (CAS 18619-18-6)
- 2-((4-Chlorophenyl)thio)acetic acid (CAS 3405-88-7)
- 2-[(3-chlorophenyl)sulfanyl]acetic acid (CAS 3996-38-1)
- 2-(4-Chlorophenyl)-1H-pyrrole-3-carbonitrile (CAS 122453-02-5)
- 2-[1-(4-chlorophenyl)ethylidene]malononitrile (CAS 3111-60-2)
- 4-(2-Chlorophenyl)-1H-pyrrole-3-carbonitrile (CAS 74738-15-1)
- 4-(3-Chlorophenyl)-1H-pyrrole-3-carbonitrile (CAS 74738-16-2)
Recommended Standards
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- 2',3'-DICHLOROPROPIOPHENONE (CAS 213382-05-9)
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- 2-(4-(Difluoromethyl)-2-iodo-6-(trifluoromethoxy)pyridin-3-yl)acetic acid (CAS 1804744-83-9)
- 2-(6-(Dimethylamino)pyridazin-3-yl)-2-phenylacetonitrile (CAS 303997-53-7)
- Tandutinib Impurity 1 (CAS 288383-74-4)
- 3-(Cyclohexylmethyl)-2-hydroxy-N,N-dimethylbenzamide (CAS 1243371-71-2)
- Finerenone Impurity 95 (CAS CATO-C4X-288095)
- 2-((Trifluoromethoxy)methyl)piperidine (CAS 1208080-29-8)
- 2-(1-Aminoethyl)-1,3-thiazole-4-carboxylic acid hydrochloride (CAS 1087345-72-9)
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