5-Bromo-6-methylpyrimidin-2(1H)-one hydrobromide CAS 63331-36-2

Description

Compared with other compounds in its class, the molecular weight of 269.92 g/mol gives 5-Bromo-6-methylpyrimidin-2(1H)-one hydrobromide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

5-Bromo-6-methylpyrimidin-2(1H)-one hydrobromide (CAS 63331-36-2), molecular formula C5H5BrN2OHBr and molecular weight 269.92 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 5-Bromo-6-methylpyrimidin-2(1H)-one hydrobromide (C5H5BrN2OHBr) is characterized by an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5-Bromo-6-methylpyrimidin-2(1H)-one hydrobromide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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