[1,3]Dioxolo[4,5-g]quinolin-6(5H)-one CAS 6335-90-6
| CAS No. | 6335-90-6 |
| Molecular Formula | C15H18Cl2N2O4 |
| Molecular Weight | 361.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), [1,3]Dioxolo[4,5-g]quinolin-6(5H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies [1,3]Dioxolo[4,5-g]quinolin-6(5H)-one (CAS 6335-90-6), a certified reference material (molecular formula C15H18Cl2N2O4, MW 361.22 g/mol) for analytical method development and quality control.
[1,3]Dioxolo[4,5-g]quinolin-6(5H)-one (C15H18Cl2N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H18Cl2N2O4 |
| Molecular Weight | 361.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dioxolo Standards
- N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-2-bromobenzamide (CAS 892854-49-8)
- N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-2-(2,5-dioxopyrrolidin-1-yl)acetamide (CAS 892851-42-2)
- N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-2-methoxybenzamide (CAS 892849-11-5)
- 1-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-3-(o-tolyl)urea (CAS 1226440-92-1)
- (5-([1,3]Dioxolo[4,5-f]isoquinolin-8-yl)benzo[d][1,3]dioxol-4-yl)methanol (CAS 164991-68-8)
- [1,3]Dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridine (CAS 522-30-5)
- N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-1,3-dimethyl-1H-pyrazole-5-carboxamide (CAS 1013796-55-8)
- N-([1,3]Dioxolo[4',5':4,5]benzo[1,2-d]thiazol-6-yl)-4-fluorobenzamide (CAS 892854-05-6)
Recommended Standards
- (4-(N-Cyclopropyl-N-(4-methoxybenzyl)sulfamoyl)phenyl)boronic acid (CAS 913835-89-9)
- 1-(2-Chloroacetyl)-9b-(4-chlorophenyl)-1,2,3,9b-tetrahydro-5H-imidazo[2,1-a]isoindol-5-one (CAS 27269-37-0)
- (3-(N-Cyclopropyl-N-(4-methoxybenzyl)sulfamoyl)phenyl)boronic acid (CAS 913836-07-4)
- 1-(3-(2,4-Dichlorophenyl)acryloyl)-5-phenylpyrazolidin-3-one (CAS 821773-11-9)
- Pentaerythritol-d (CAS 82414-60-6)
- 4-Bromo-2,5-dimethylnitrobenzene (CAS 15540-81-5)
- N-Benzoyl-O,α-dimethyl-D-tyrosine Methyl Ester (CAS 172168-14-8)
- 2-Amino-N-(4-methoxybenzyl)-N-methylacetamide (CAS 1178707-67-9)
- Ethyl 3,7-dimethyloct-2-enoate (CAS 266302-61-8)
- 3-Amino-4-(tert-butylamino)benzonitrile (CAS 320406-79-9)
- Benzyl (1-aminocyclopropane-1-carbonyl)carbamate (CAS 108056-97-9)
- Bis[3-(phenylimino)butyrophenonato]copper (CAS 14482-83-8)
- (Z)-6-chloro-N'-hydroxy-1H-indole-3-carboximidamide (CAS 889942-64-7)
- Semaglutide Impurity 160 (x TFA Salt) (CAS CATO-C4X-2226160)
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