3-Methyl-2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinoline-4-carboxylic acid CAS 6336-87-4
| CAS No. | 6336-87-4 |
| Molecular Formula | C18H11NO4 |
| Molecular Weight | 305.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-Methyl-2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinoline-4-carboxylic acid.
CATO supplies 3-Methyl-2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinoline-4-carboxylic acid (CAS 6336-87-4), a certified reference material (molecular formula C18H11NO4, MW 305.28 g/mol) for analytical method development and quality control.
The molecular framework of 3-Methyl-2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinoline-4-carboxylic acid (C18H11NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-Methyl-2,7-dioxo-3,7-dihydro-2H-naphtho[1,2,3-de]quinoline-4-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H11NO4 |
| Molecular Weight | 305.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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Recommended Standards
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- 2-((2,5-Dimethoxyphenyl)amino)-2-oxoethyl furan-3-carboxylate (CAS 923754-57-8)
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- Boc-l-2,4-dimethylphenylalanine (CAS 849440-31-9)
- Ethyl 2-(pyrrolidyl)propionate (CAS 26846-86-6)
- 2-Bromo-4-cyclopropoxy-3-(methylthio)pyridine (CAS 1243397-16-1)
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- 2-(Difluoromethyl)-5-nitropyridine-3-carboxylic acid (CAS 1805224-32-1)
- (2S,3S)-2-(4-Ethoxyphenyl)-1-ethyl-6-oxopiperidine-3-carboxylic acid (CAS 1212404-60-8)
- Tau Peptide (295-309) trifluoroacetate salt (CAS 330456-46-7)
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