4-Hydroxy-3-nitrophenylacetonitrile CAS 63367-08-8
| CAS No. | 63367-08-8 |
| Molecular Formula | C8H6N2O3 |
| Molecular Weight | 178.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Hydroxy-3-nitrophenylacetonitrile.
CATO supplies 4-Hydroxy-3-nitrophenylacetonitrile (CAS 63367-08-8), a certified reference material (molecular formula C8H6N2O3, MW 178.14 g/mol) for analytical method development and quality control.
The molecular framework of 4-Hydroxy-3-nitrophenylacetonitrile (C8H6N2O3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H6N2O3 |
| Molecular Weight | 178.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Hydroxy Standards
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Recommended Standards
- 4-Hydroxy-1H-indazole-3-carboxylic acid (CAS 885519-93-7)
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- 4-Isocyanato-2-methyl-1-nitrobenzene (CAS 56021-25-1)
- 4-(tert-Butyl)-N-ethylbenzohydrazide (CAS 2573850-19-6)
- 5-(((7-Chloroquinolin-4-yl)thio)methyl)-4-methyl-4H-1,2,4-triazole-3-thiol (CAS 845885-91-8)
- 2-(3,4-Dimethoxyphenyl)-N-methyl-d3-ethylamine (CAS 152561-88-1)
- TERT-BUTYL 2,2,3,3,9,9,10,10-OCTAMETHYL-4,8-DIOXA-3,9-DISILAUNDECAN-6-YLCARBAMATE (CAS 1951440-94-0)
- 3-(aminomethyl)-1-methyl-1,2-dihydropyrazin-2-one dihydrochloride (CAS 2060060-78-6)
- 4-(Dimethylamino)-3-methoxyphenol (CAS 115167-16-3)
- 3,5,7-Trimethoxyflavone (CAS 26964-29-4)
- 7-Bromo-2-chloro-1H-benzo[d]imidazole-5-carbonitrile (CAS 1388068-26-5)
- 2-Chloro-N-(2,3-dihydro-1H-inden-2-yl)acetamide (CAS 36851-11-3)
- Cycloaspeptide A (CAS 109171-13-3)
Why CATO?
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