2-Chloro-4-methyl-quinoline CAS 634-47-9
| CAS No. | 634-47-9 |
| Molecular Formula | C10H8ClN |
| Molecular Weight | 177.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-Chloro-4-methyl-quinoline (C10H8ClN) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies 2-Chloro-4-methyl-quinoline (CAS 634-47-9), a certified reference material (molecular formula C10H8ClN, MW 177.63 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-4-methyl-quinoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H8ClN |
| Molecular Weight | 177.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 3-Chloro-2-methylquinoline (CAS 10222-49-8)
- 8-Chloro-7-methylquinoline (CAS 102653-25-8)
- 5-Chloro-2-methoxynicotinaldehyde (CAS 103058-88-4)
- 3-Chloro-7-methylisoquinoline (CAS 1033201-77-2)
- 6-chloro-4-methoxy-pyridine-2-carbaldehyde (CAS 1060805-05-1)
- 4-chloro-3-methyl-isoxazolo[4,5-d]pyridazine (CAS 106584-75-2)
- 7-chloro-3-methyl-isoxazolo[4,5-d]pyridazine (CAS 106584-76-3)
- 2-Chloro-N-(oxan-4-yl)acetamide (CAS 1154931-91-5)
Recommended Standards
- 2-Chloro-3-(2-cyanophenyl)-1-propene (CAS 731772-23-9)
- 2-Chloro-5-methylquinoline (CAS 23952-31-0)
- 2-Chloro-1-(4-morpholinyl)-1-propanone (CAS 54022-76-3)
- 2-Chloro-6-methylquinoline (CAS 4295-11-8)
- 5,6-Dimethoxyisoquinolin-1(2H)-one (CAS 630423-25-5)
- 2-Oxo-4-phenylbutyroyl chloride (CAS 1706437-47-9)
- 3-(Phenylsulfonyl)-8-azabicyclo[3.2.1]Octane (CAS 1135190-13-4)
- Cyclohexylchloromethyl phenyl Sulfoxide (CAS 104354-60-1)
- Ethyl 5-chloro-3-methylthieno[2,3-c]pyridine-2-carboxylate (CAS 1268834-50-9)
- 3-Chloro-8-(trifluoromethyl)imidazo[1,2-a]pyridine-2-carboxylic acid (CAS 1237838-81-1)
- (3-Methyl-4-(pyrrolidin-1-yl)phenyl)methanamine (CAS 1184165-51-2)
- Methyl 2-(5-chlorothiophen-2-yl)propanoate (CAS 1513645-52-7)
- N-(4-(benzyloxy)phenyl)-2-bromoacetamide (CAS 349120-98-5)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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