5-(4-((2-Chlorobenzyl)oxy)phenyl)-N'-(4-ethoxybenzylidene)-1H-pyrazole-3-carbohydrazide CAS 634897-17-9
| CAS No. | 634897-17-9 |
| Molecular Formula | C26H23ClN4O3 |
| Molecular Weight | 474.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
5-(4-((2-Chlorobenzyl)oxy)phenyl)-N'-(4-ethoxybenzylidene)-1H-pyrazole-3-carbohydrazide (CAS 634897-17-9) is a high-purity analytical reference standard with the molecular formula C26H23ClN4O3 and a molecular weight of 474.94 g/mol.
The molecular framework of 5-(4-((2-Chlorobenzyl)oxy)phenyl)-N'-(4-ethoxybenzylidene)-1H-pyrazole-3-carbohydrazide (C26H23ClN4O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C26H23ClN4O3 |
| Molecular Weight | 474.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chlorobenzyl Standards
- 5-(4-((2-Chlorobenzyl)oxy)phenyl)-N'-(2-ethoxybenzylidene)-1H-pyrazole-3-carbohydrazide (CAS 634897-07-7)
- 3-(2-((4-Chlorobenzyl)oxy)phenyl)-1-(naphthalen-1-ylsulfonyl)-1H-pyrazole (CAS 477713-42-1)
- (E)-2-((4-chlorobenzyl)thio)quinoline-3-carbaldehyde O-(4-(tert-butyl)benzyl) oxime (CAS 692287-20-0)
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- (4-(((4-Chlorobenzyl)sulfonyl)methyl)-4-hydroxypiperidin-1-yl)(3-(trifluoromethyl)phenyl)methanone (CAS 866019-54-7)
- 3-((4-Chlorobenzyl)thio)-4-phenyl-5-((3-(trifluoromethyl)phenoxy)methyl)-4H-1,2,4-triazole (CAS 383145-75-3)
- 2-((5-((4-Chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(2-(trifluoromethyl)phenyl)acetamide (CAS 578718-77-1)
- 2-((5-((3-Chlorobenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)-N-(3,4-dichlorophenyl)acetamide (CAS 353254-79-2)
Recommended Standards
- alpha-[6-(Di-Boc-amino)-3-pyridyl]-5-chloro-1H-pyrrolo[2,3-b]pyridine-3-methanol (CAS 2040295-05-2)
- 4-{[(3,5-dimethylphenyl)carbamoyl]methyl}phenyl 3-(2-chlorophenyl)-5-methyl-1,2-oxazole-4-carboxylate (CAS 439096-83-0)
- AP-768 (CAS 780763-95-3)
- METHYL 1-(2-CHLOROPHENYL)-5-(5-(3-(METHYLSULFONYL)PHENYL)-1,3,4-THIADIAZOL-2-YL)-1H-PYRAZOLE-3-CARBOXYLATE (CAS 1454288-71-1)
- 7-(Difluoromethoxy)quinolin-2-ol (CAS 1261458-20-1)
- 2-(2-Chloro-4-fluorophenyl)acetimidamide (CAS 1016867-37-0)
- 2-[(4-Bromophenyl)sulfanyl]-6-phenylpyridine-3-carbonitrile (CAS 252058-87-0)
- 2,5-Dihydro-2,2,5,5-tetramethyl-3-[[(methylsulfonyl)thio]methyl]-4-(3-pyridinyl)-1H-pyrrol-1-yloxy (CAS 1379779-19-7)
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- N-(2-Cyano-3-methylbutan-2-yl)-2-((4-isopropyl-5-(4-methoxyphenyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 745023-50-1)
- 75181-07-6 CTK5E1240 Zirconium,trichloro[(1,2,3,4,5-h)-1,2,3,4,5-pentamethyl-2,4-cyclopentadien-1-yl]- (CAS 75181-07-6)
- Peptide 433 (CAS CATO-CPTD788433)
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