4-Amino-3-chloro-5-(trifluoromethyl)benzoyl chloride CAS 63498-15-7
| CAS No. | 63498-15-7 |
| Molecular Formula | C8H4Cl2F3NO |
| Molecular Weight | 258.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 258.02 g/mol gives 4-Amino-3-chloro-5-(trifluoromethyl)benzoyl chloride distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-Amino-3-chloro-5-(trifluoromethyl)benzoyl chloride (CAS 63498-15-7), molecular formula C8H4Cl2F3NO and molecular weight 258.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Amino-3-chloro-5-(trifluoromethyl)benzoyl chloride (C8H4Cl2F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-Amino-3-chloro-5-(trifluoromethyl)benzoyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H4Cl2F3NO |
| Molecular Weight | 258.02 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Amino Standards
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Recommended Standards
- 2,6-Dichloro-3-(trifluoromethyl)benzamide (CAS 53012-81-0)
- N-(2,5-Dichlorophenyl)-2,2,2-trifluoroacetamide (CAS 328-11-0)
- N-(3,4-Dichlorophenyl)-2,2,2-trifluoroacetamide (CAS 64694-85-5)
- 2,3-Dichloro-6-(trifluoromethyl)benzamide (CAS 186517-38-4)
- (R)-3-(3-Bromobenzyl)piperazin-2-one (CAS 1240586-56-4)
- 4-(5-Chlorothiophen-2-yl)pyrimidin-2(1H)-imine (CAS 855308-65-5)
- Methyl 3-nitro-4-sulfamoylbenzoate (CAS 162010-79-9)
- Bicyclo[3.1.0]hexane (CAS 285-58-5)
- 4-Amino-2'-methoxy[1,1'-biphenyl]-3-carboxylic acid (CAS 893735-62-1)
- 2-[4-(4-Piperidinyl)-1-piperazinyl]-1-ethanol trihydrochloride (CAS 1609400-42-1)
- 6-Bromo-3-cyclopropoxy-N,N-dimethylpicolinamide (CAS 1243403-40-8)
- 1-(1-Ethoxy-4-ethylcyclohexyl)-N-methylmethanamine (CAS 1249024-58-5)
- 1-(azidomethyl)-2-chlorobenzene (CAS 63777-70-8)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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