6-(4-Hydroxy-3-methyl-1H-pyrazol-1-yl)naphthalene-2-sulfonic acid CAS 6357-97-7
| CAS No. | 6357-97-7 |
| Molecular Formula | C14H12N2O4S |
| Molecular Weight | 304.32 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-(4-Hydroxy-3-methyl-1H-pyrazol-1-yl)naphthalene-2-sulfonic acid (CAS 6357-97-7), molecular formula C14H12N2O4S and molecular weight 304.32 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 6-(4-Hydroxy-3-methyl-1H-pyrazol-1-yl)naphthalene-2-sulfonic acid (C14H12N2O4S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H12N2O4S |
| Molecular Weight | 304.32 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Hydroxy Standards
- Methyl 4-hydroxy-8-isopropyl-6,7-dimethoxy-2-naphthoate (CAS 1415564-88-3)
- 2-Hydroxy-6-(2-naphthalen-1-yl-vinyl)-benzoic acid methyl ester (CAS 365542-22-9)
- 2-Hydroxy-n-[4-(4-pyridinylmethyl)phenyl]benzamide (CAS 341018-61-9)
- 3-(3-Hydroxy-4-methoxyphenyl)-1-(naphthalen-2-yl)prop-2-en-1-one (CAS 944443-38-3)
- 4-Hydroxy-3-(imino(phenyl)methyl)-1-methyl-6-phenylpyridin-2(1H)-one (CAS 60986-58-5)
- 4-Hydroxy-3-(imino(phenyl)methyl)-1-methyl-6-phenylpyridin-2(1H)-one (CAS 87829-34-3)
- 4-Hydroxy-6-(4-methoxyphenyl)-2-(2-pyridinyl)-5-pyrimidinecarbonitrile (CAS 320418-61-9)
- 5-[(4-Hydroxy-3-methoxy-5-methylphenyl)methylene]-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione (CAS 860644-62-8)
Recommended Standards
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- 5-(4-Nitrobenzoyl)-N2-(prop-2-en-1-yl)-1,3-thiazole-2,4-diamine (CAS 478247-68-6)
- 7-(4-Fluorophenyl)-5-phenyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine (CAS 243665-87-4)
- 1-(5-Chloro-1-(3-ethoxypropyl)-1H-benzo[d]imidazol-2-yl)ethan-1-ol (CAS 1243803-67-9)
- N-(6-Bromo-3-(2-ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)cyclopropanecarboxamide (CAS 865162-82-9)
- 3-Amino-5-ethyl-4,6-dimethylthieno[2,3-b]pyridine-2-carbonitrile (CAS 312535-65-2)
- 3-Butyloxetan-3-ol (CAS 1439367-52-8)
- 1-benzyl-5-methylpyrrolidine-2,4-dione (CAS 114473-97-1)
- (S)-1-(3-chloro-4-fluorophenyl)but-3-en-1-amine (CAS 1269780-90-6)
- 2,2,2-Trifluoro-1-(3-pyridyl)ethanone (CAS 33284-21-8)
- (2|A,5|A,6|A,18|A)-3,4-DidehydroIbogamine-18-carboxylic Acid 63944-54-7 Catharanthinic Acid (CAS 63944-54-7)
- 4-Methyl-[1,4]bipiperidinyltrifluoroacetate (CAS 436099-88-6)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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