6-Chloro-2-methyl-5-nitropyrimidin-4-amine CAS 63586-33-4
| CAS No. | 63586-33-4 |
| Molecular Formula | C5H5ClN4O2 |
| Molecular Weight | 188.57 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-methyl-5-nitropyrimidin-4-amine (CAS 63586-33-4) is a high-purity analytical reference standard with the molecular formula C5H5ClN4O2 and a molecular weight of 188.57 g/mol.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 6-Chloro-2-methyl-5-nitropyrimidin-4-amine is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 188.57 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-Chloro-2-methyl-5-nitropyrimidin-4-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C5H5ClN4O2 |
| Molecular Weight | 188.57 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related Chloro Standards
- 2-Chloro-5-methoxy-3-nitropyridine (CAS 1003711-55-4)
- 4-Chloro-3,5-dihydroxybenzoic acid (CAS 102338-87-4)
- 2-Chloro-3-methoxy-4-nitropyridine (CAS 109613-91-4)
- 2-Chloro-4-methyl-5-nitropyridine 1-oxide (CAS 1253378-56-1)
- 2-Chloro-4-methoxypyrimidine-5-carboxylic acid (CAS 1375064-78-0)
- 6-Chloro-4-methoxypyridazine-3-carboxylic acid (CAS 1517036-80-4)
- 2-(4-chloro-5-formylfuran-2-yl)acetic acid (CAS 1525671-23-1)
- 5-Chloro-3-methoxy-2-nitropyridine (CAS 152684-28-1)
Recommended Standards
- 6-Chloro-2-methoxypyrimidine-4-carboxylic acid (CAS 944902-07-2)
- 6-Chloro-3-hydrazinylpyridazine-4-carboxylic acid (CAS 77813-57-1)
- 5-chloro-6-methyl-3-nitropyridin-2(1H)-one (CAS 56960-83-9)
- 6-Chloro-N-methyl-5-nitro-4-pyrimidinamine (CAS 23126-82-1)
- 4-(4-Isopropylphenoxy)aniline (CAS 64969-83-1)
- N-((1,3-Diphenyl-1H-pyrazol-5-yl)carbamothioyl)benzamide (CAS 70027-35-9)
- Propargyl-PEG4-tetra-Ac-beta-D-glucose (CAS 1360446-31-6)
- Cefotiam Impurity 53 (CAS CATO-C4X-120453)
- 1-Cyclobutylpiperidin-4-one hydrochloride (CAS 1210824-86-4)
- 1,2-Bis(di-tert-butylphosphinemethyl)benzene (CAS 121954-50-5)
- Ethyl 7-(2-chloro-6-fluorophenyl)-7-oxoheptanoate (CAS 951887-14-2)
- (2R,4R)-1-(tert-Butoxycarbonyl)-4-(difluoromethyl)pyrrolidine-2-carboxylic acid (CAS 2301881-91-2)
- Tert-butyl (S)-8-amino-6-oxa-2-azaspiro[3.4]Octane-2-carboxylate (CAS 2306248-92-8)
- Insulin Degludec Impurity 17 (CAS CATO-C4X-215717)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com