Diethyl Isophthalate CAS 636-53-3
| CAS No. | 636-53-3 |
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Diethyl Isophthalate (CAS 636-53-3), molecular formula C12H14O4 and molecular weight 222.24 g/mol, is a CATO reference standard with documented purity and traceability.
Diethyl Isophthalate (C12H14O4) contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
Related Diethyl Standards
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Recommended Standards
- Flavone (CAS 525-82-6)
- 2-Methylanthraquinone (CAS 84-54-8)
- 2-Phenyl-1,3-indandione (CAS 83-12-5)
- Landiolol Impurity 67 (CAS CATO-C4X-262167)
- 3-Cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine (CAS 2096333-32-1)
- 5-Chloro-2-methoxy-1,8-naphthyridine (CAS 2289740-41-4)
- 4-(5H,6h,7h,8h-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)pyridine (CAS 1004303-68-7)
- 2-Bromo-1-(bromomethyl)-3-iodobenzene (CAS 1261649-03-9)
- 2-(Phenoxymethyl)butane-1-sulfonyl chloride (CAS 1481415-68-2)
- Benzyl 2-(trifluoromethyl)piperazine-1-carboxylate (CAS 2387600-86-2)
- Methyl 4-(bromomethyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate (CAS 1626407-50-8)
- 2-(3-Amino-1h-pyrazol-1-yl)-N-(1-methoxypropan-2-yl)acetamide (CAS 1251313-55-9)
- Boc-Lys-OMe (hydrochloride) (CAS 99532-86-2)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
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