(S)-2-(2-chlorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride CAS 637020-76-9
| CAS No. | 637020-76-9 |
| Molecular Formula | C12H14ClNO2 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
(S)-2-(2-chlorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride (CAS 637020-76-9) is a high-purity analytical reference standard with the molecular formula C12H14ClNO2HCl and a molecular weight of 276.16 g/mol.
The molecular framework of (S)-2-(2-chlorobenzyl)pyrrolidine-2-carboxylic acid hydrochloride (C12H14ClNO2HCl) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO2 HCl |
| Molecular Weight | 276.16 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related S Standards
- 1-(4-Chlorobenzyl)-5-methyl-3-nitro-1h-pyrazole (CAS 1001510-38-8)
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Recommended Standards
- Methyl 2-(bromomethyl)-5-chloro-4-methoxybenzoate (CAS 109803-49-8)
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- Hydrocortisone Impurity (CAS 20287-97-2)
- 2,2-Difluoro-2-(4-isopropoxyphenyl)acetic acid (CAS 1339100-72-9)
- Diammonium 2,2'-dithiodiacetate (CAS 68223-93-8)
- diethyl 2-[{[(benzyloxy)carbonyl]amino}(3-chlorophenyl)methyl]malonate (CAS 1033463-15-8)
- 2-(Bromomethyl)-3-chloronaphthalene (CAS 99867-10-4)
- 1-[trans-4-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]cyclohexyl]-4-iodo-1H-pyrazole (CAS 1257997-18-4)
- 4-Detrifluoroethoxy-4-methylsulfonyl Lansoprazole Sulfone (CAS 1648891-88-6)
- Des-Pro36-Tirzepatide (CAS CATO-CPTD788937)
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