6-Chloro-2H-benzo[b][1,4]thiazin-3(4H)-one CAS 6376-70-1
| CAS No. | 6376-70-1 |
| Molecular Formula | C8H6ClNOS |
| Molecular Weight | 199.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
6-Chloro-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 6376-70-1) is a high-purity analytical reference standard with the molecular formula C8H6ClNOS and a molecular weight of 199.66 g/mol.
Based on its molecular formula C8H6ClNOS, 6-Chloro-2H-benzo[b][1,4]thiazin-3(4H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 199.66 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), 6-Chloro-2H-benzo[b][1,4]thiazin-3(4H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H6ClNOS |
| Molecular Weight | 199.66 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 8-Chloro-2H-benzo[b][1,4]thiazin-3(4H)-one (CAS 100638-21-9)
- 6-Chloro-2-Methylthieno[3,2-d]pyrimidin-4-amine (CAS 1017789-18-2)
- 3-Chloro-4-methoxy-1,2-benzisothiazole (CAS 103486-06-2)
- 3-Chloro-6-methoxy-1,2-benzothiazole (CAS 103486-07-3)
- 6-Chloro-2-(methylthio)benzo[d]oxazole (CAS 1071296-64-4)
- 4-chloro-2-(methylsulfanyl)pyrrolo[2,1-f][1,2,4]triazine (CAS 1120214-78-9)
- 4-Chloro-2-methyl-6-(methylthio)pyrimidine-5-carbonitrile (CAS 112969-42-3)
- 2-Chloro-7-methoxybenzo[d]thiazole (CAS 1175277-80-1)
Recommended Standards
- 6-Chloro-2-(methylthio)-3H-imidazo[4,5-c]pyridine (CAS 7205-44-9)
- 6-Chloro-2-hydrazinylbenzo[d]thiazole (CAS 51011-54-2)
- 5-Chloro-7-methyl-1,3-benzoxazole-2-thiol (CAS 93794-45-7)
- 6-Chloro-3-methylbenzo[d]thiazol-2(3H)-one (CAS 63754-98-3)
- 6-chloro-4-(trifluoromethyl)pyridin-3-amine (CAS 1211590-44-1)
- 4-Oxo-1,2-diphenylazetidine-2-carboxylic acid (CAS 13327-23-6)
- Dicyclohexyl Phthalate-d4 (CAS 358731-25-6)
- 3-(1H-1,2,3-triazol-1-yl)propanoic acid (CAS 4332-45-0)
- Tetrahydro-2H-thiopyran-2-one (CAS 1003-42-5)
- 2-(2,3-Dichlorophenyl)-3-hydroxypyridine (CAS 1261994-88-0)
- 1-Butanoylpyrrolidine-2-carboxylic acid (CAS 23500-17-6)
- (2S,3R)-3-Aminotetrahydrofuran-2-carboxylic acid hydrochloride (CAS 149409-90-5)
- tert-Butyl 2-(4-aminophenyl)-2-methylpropanoate (CAS 1532807-04-7)
- Semaglutide (CAS 910463-68-2（free base）)
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