2-(Benzo[d]thiazol-2-yl)-3-((2-fluorophenyl)amino)acrylonitrile CAS 637748-58-4
| CAS No. | 637748-58-4 |
| Molecular Formula | C16H10FN3S |
| Molecular Weight | 295.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(Benzo[d]thiazol-2-yl)-3-((2-fluorophenyl)amino)acrylonitrile (C16H10FN3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies 2-(Benzo[d]thiazol-2-yl)-3-((2-fluorophenyl)amino)acrylonitrile (CAS 637748-58-4), a certified reference material (molecular formula C16H10FN3S, MW 295.33 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2-(Benzo[d]thiazol-2-yl)-3-((2-fluorophenyl)amino)acrylonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H10FN3S |
| Molecular Weight | 295.33 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 4-Chloro-3-morpholin-4-yl-benzoic acid (CAS 886501-46-8)
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