2-Dichloromethylbenzonitrile CAS 64148-19-2
| CAS No. | 64148-19-2 |
| Molecular Formula | C8H5Cl2N |
| Molecular Weight | 186.04 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Dichloromethylbenzonitrile.
2-Dichloromethylbenzonitrile (CAS 64148-19-2) is a high-purity analytical reference standard with the molecular formula C8H5Cl2N and a molecular weight of 186.04 g/mol.
2-Dichloromethylbenzonitrile (C8H5Cl2N) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-Dichloromethylbenzonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H5Cl2N |
| Molecular Weight | 186.04 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- 3,4-Dichlorophenylacetonitrile (CAS 3218-49-3)
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- N-(3-morpholinopropyl)-2-(1H-1,2,4-triazol-1-yl)acetamide (CAS 439110-53-9)
- 2-(4-Chlorothiophen-2-yl)ethan-1-ol (CAS 1370047-44-1)
- 24,25-Dihydroxy VD3 (CAS 40013-87-4)
- 2-Chloro-3,5-dimethylpyrazine (CAS 38557-72-1)
- 3-(4-Methyl-1,2,5-oxadiazol-3-yl)-1,2,4-oxadiazole-5-carboxamide (CAS 890096-09-0)
- 2-(3-Chlorophenyl)isoindolin-1-imine (CAS 321686-44-6)
- Semaglutide Impurity 191 (CAS CATO-C4X-2226191)
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