8-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole CAS 64172-41-4
| CAS No. | 64172-41-4 |
| Molecular Formula | C12H14N2 |
| Molecular Weight | 186.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 8-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole.
8-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (CAS 64172-41-4) is a high-purity analytical reference standard with the molecular formula C12H14N2 and a molecular weight of 186.25 g/mol.
Structurally, 8-Methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole (C12H14N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 7.0, corresponding to approximately 7 ring(s) or double-bond equivalent(s). With a molecular weight of 186.25 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N2 |
| Molecular Weight | 186.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Methyl Standards
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- tetrahydro-pyran-4-carboxylic acid tert-butyl ester (CAS 1058129-65-9)
- 1-Methyl-6,7,8,9-tetrahydro-1H-naphtho[1,2-d]imidazole (CAS 108629-36-3)
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Recommended Standards
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- 9B-methyl-1,2,3,9b-tetrahydrodibenzo[b,d]furan (CAS 89228-51-3)
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- 2-Bromo-6,7-dihydro-5H-pyrrolo[1,2-a]imidazole (CAS 1525619-20-8)
- 2-Amino-7-methyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1239648-57-7)
- N-((2-chloropyridin-4-yl)methyl)-N-propylcyclopropanamine (CAS 1250350-65-2)
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