2,3-Dihydro-8-(trifluoromethyl)pyrrolo[2,1-b]quinazolin-9(1H)-one CAS 642491-87-0
| CAS No. | 642491-87-0 |
| Molecular Formula | C12H9F3N2O |
| Molecular Weight | 254.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO supplies 2,3-Dihydro-8-(trifluoromethyl)pyrrolo[2,1-b]quinazolin-9(1H)-one (CAS 642491-87-0), a certified reference material (molecular formula C12H9F3N2O, MW 254.21 g/mol) for analytical method development and quality control.
The molecular framework of 2,3-Dihydro-8-(trifluoromethyl)pyrrolo[2,1-b]quinazolin-9(1H)-one (C12H9F3N2O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2,3-Dihydro-8-(trifluoromethyl)pyrrolo[2,1-b]quinazolin-9(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9F3N2O |
| Molecular Weight | 254.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Dihydro Standards
- 2-Butyl-2,3-dihydro-1,2-benzoselenazol-3-one (CAS 60940-32-1)
- 1-(1,2-Dihydro-4-methyl-2-oxo-7-quinolinyl)-1H-pyrrole-2,5-dione 1076199-75-1 Carbostyril Maleimide (CAS 1076199-75-1)
- 2-[3,4-Dihydro-1(2H)-quinolinyl]nicotinic acid (CAS 1017200-69-9)
- 2-[3,4-Dihydro-2(1H)-isoquinolinyl]-isonicotinic acid (CAS 1019375-24-6)
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- 2-[3,4-Dihydro-2(1H)-isoquinolinyl]nicotinic acid (CAS 250739-09-4)
- 4-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-7-yl)benzaldehyde (CAS 952182-92-2)
Recommended Standards
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- 5-Cyclopropoxy-N,N-dimethyl-4-(trifluoromethyl)pyridin-3-amine (CAS 1243361-30-9)
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