3-[3-(Trifluoromethyl)phenyl]piperidine hydrochloride CAS 64321-43-3
| CAS No. | 64321-43-3 |
| Molecular Formula | C12H14F3N |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-[3-(Trifluoromethyl)phenyl]piperidine hydrochloride.
3-[3-(Trifluoromethyl)phenyl]piperidine hydrochloride (CAS 64321-43-3) is a high-purity analytical reference standard with the molecular formula C12H14F3NHCl and a molecular weight of 265.70 g/mol.
Structurally, 3-[3-(Trifluoromethyl)phenyl]piperidine hydrochloride (C12H14F3NHCl) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 4.0, corresponding to approximately 4 ring(s) or double-bond equivalent(s). With a molecular weight of 265.70 g/mol, it falls into the medium-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-[3-(Trifluoromethyl)phenyl]piperidine hydrochloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H14F3N HCl |
| Molecular Weight | 265.70 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidin-3-ol hydrochloride (CAS 1000198-74-2)
- 3-(4-(Trifluoromethyl)phenyl)pyrrolidine (CAS 1000198-76-4)
- (2-Methyl-4-(trifluoromethyl)thiazol-5-yl)methanol (CAS 1000339-72-9)
- methyl 3-((4-(trifluoromethyl)piperidin-1-yl)methyl)benzoate (CAS 1000339-86-5)
- methyl 4-(2-(4-(trifluoromethyl)piperidin-1-yl)ethoxy)benzoate (CAS 1000339-87-6)
- 2-(4-(trifluoromethyl)piperidin-1-yl)thiazole-5-carbaldehyde (CAS 1000339-88-7)
- 3-(2-(4-(trifluoromethyl)piperidin-1-yl)ethyl)benzaldehyde (CAS 1000339-89-8)
- 4-(2-(4-(trifluoromethyl)piperidin-1-yl)acetyl)-1H-pyrrole-2-carbaldehyde (CAS 1000339-90-1)
Recommended Standards
- 5-(5,6-dimethyl-1H-1,3-benzodiazol-2-yl)quinoline (CAS 1354949-91-9)
- 4-Bromo-2-methylpyrazolo[1,5-a]pyridine (CAS 2857113-38-1)
- 4-(3,5-Dimethylphenyl)piperidine (CAS 80836-03-9)
- 5-Bromo-4,7-difluoro-1H-indazole (CAS 1459253-84-9)
- Palladate(1-), diamminedichloro- (CAS 53899-86-8)
- Methyl 2-(4-formylphenyl)-2-hydroxyacetate (CAS 2101791-93-7)
- 7-Bromo-5-fluoroisatin (CAS 380431-78-7)
- 1-(3-(4-Aminophenyl)-1,2,4-oxadiazol-5-yl)guanidine (CAS 88541-01-9)
- 4-(3-(Trifluoromethoxy)phenyl)-1,2,3,6-tetrahydropyridine (CAS 1211874-90-6)
- Fas C- Terminal Tripeptide (CAS 189109-90-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com