2-Butyl-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylic acid CAS 64321-85-3
| CAS No. | 64321-85-3 |
| Molecular Formula | C15H14F3NO3 |
| Molecular Weight | 313.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 2-Butyl-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 2-Butyl-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 64321-85-3), a certified reference material (molecular formula C15H14F3NO3, MW 313.27 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2-Butyl-4-hydroxy-8-(trifluoromethyl)quinoline-3-carboxylic acid is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 313.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C15H14F3NO3 |
| Molecular Weight | 313.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Butyl Standards
- 4-Hydroxy-2-isobutyl-8-(trifluoromethyl)quinoline-3-carboxylic acid (CAS 64321-90-0)
- 1-[3-hydroxy-3-(trifluoromethyl)pyrrolidin-1-yl]-2-{1H-pyrrolo[2,3-b]pyridin-3-yl}ethan-1-one (CAS 2177634-84-1)
- 6-Hydroxy-4,7-dimethoxy-N-phenylbenzofuran-5-carboxamide (CAS 88258-54-2)
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- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-morpholinothiophen-3-yl)boronate (CAS 1498296-07-3)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-morpholinothiophen-2-yl)boronate (CAS 2223039-99-2)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (5-(tetrahydro-2H-pyran-4-yl)thiazol-4-yl)boronate (CAS 2223033-44-9)
Recommended Standards
- 1-(Tert-butyl) 2-methyl (2S,4S)-4-hydroxy-4-(trifluoromethyl)pyrrolidine-1,2-dicarboxylate (CAS 470482-36-1)
- 2-Methoxy-6-(((4-(trifluoromethoxy)phenyl)amino)methyl)phenol (CAS 306730-45-0)
- (S)-N-Cyclopentyl-N-(3,5-dichlorobenzyl)pyrrolidin-3-amine (CAS 820980-29-8)
- 3-(Benzo[d][1,3]dioxol-5-yl)-1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione (CAS 52199-05-0)
- 6-Methyl-2-((2-phenoxyethyl)thio)-5,6,7,8-tetrahydro-1,6-naphthyridine-3-carbonitrile (CAS 445384-27-0)
- (E)-4-(1H-indol-3-yl)but-3-en-2-one (CAS 31951-75-4)
- 1-Ethyl-1H-pyrazole-3,4-dicarboxylic acid (CAS 52942-75-3)
- (R)-3-azaspiro[5.5]Undecan-8-amine dihydrochloride (CAS 2306253-23-4)
- 1219948-54-5 1407AD 2-(2-Piperidinyl)ethyl tetrahydro-2H-pyran-4-carboxylate hydrochloride C13H24ClNO3 (CAS 1219948-54-5)
- 2-(2-(2,5-Dioxopyrrolidin-1-yl)acetamido)-4,5-dimethylthiophene-3-carboxamide (CAS 896310-02-4)
- (R)-5-Chloro-7-fluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 1213668-68-8)
- 8-Bromo-5-nitroisoquinoline (CAS 252861-41-9)
- 2-(Difluoromethyl)-6-hydroxy-4-nitropyridine (CAS 1805281-40-6)
- (Tyr9)-Cholecystokinin Octapeptide (sulfated) (H-9770.0005) (CAS 96607-61-3)
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