Acetylcysteine Impurity N1 CAS 6436-58-4
| CAS No. | 6436-58-4 |
| Molecular Formula | C6H9NO2S |
| Molecular Weight | 159.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Acetylcysteine Impurity N1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Acetylcysteine Impurity N1 (CAS 6436-58-4) is a certified pharmaceutical impurity reference standard with the molecular formula C6H9NO2S and a molecular weight of 159.21 g/mol.
Structurally, Acetylcysteine Impurity N1 (C6H9NO2S) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 159.21 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C6H9NO2S |
| Molecular Weight | 159.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1958 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Acetylcysteine Standards
- Acetylcysteine Impurity 14 (CAS 62305-89-9)
- Acetylcysteine Impurity 37 (CAS 155172-79-5)
- Acetylcysteine Impurity 22 (CAS 60333-15-5)
- Acetylcysteine Impurity 20 (CAS CATO-C4X-153220)
- Acetylcysteine Impurity 34 (CAS 2381-08-0)
- Acetylcysteine Impurity 12 (CAS 1115-65-7)
- N-Acetylcysteine-d3 (CAS 131685-11-5)
- Acetylcysteine Impurity 41 (CAS 13100-82-8)
Recommended Standards
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- Istradefylline Impurity 7 (CAS CATO-C4X-10617)
- Cefathiamidine Impurity 13 (CAS CATO-C4X-133713)
- (5-Methoxypyrimidin-2-yl)methanamine (CAS 1553867-87-0)
- [9,9'-Bianthracene]-10-carbonitrile (CAS 103266-00-8)
- Ethyl 2-[(4-fluorophenyl)amino]acetate (CAS 2521-99-5)
- N,N'-(1,3-Phenylene)diacetamide (CAS 10268-78-7)
- 2-(Ethanesulfinyl)benzoic acid (CAS 41394-89-2)
- N,N-Dimethyl benzoimidazole-1-sulfonamide (CAS 349422-98-6)
- Polymyxin B nonapeptide (CAS 86408-36-8)
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