Diethyl 2-(3-nitropyridin-2-yl)malonate CAS 64362-41-0
| CAS No. | 64362-41-0 |
| Molecular Formula | C12H14N2O6 |
| Molecular Weight | 282.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Diethyl 2-(3-nitropyridin-2-yl)malonate (C12H14N2O6) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Diethyl 2-(3-nitropyridin-2-yl)malonate (CAS 64362-41-0), molecular formula C12H14N2O6 and molecular weight 282.25 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14N2O6 |
| Molecular Weight | 282.25 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 2 |
Related Diethyl Standards
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Recommended Standards
- Damnacanthal (CAS 477-84-9)
- 8-Carbamoyl-2-phenylimidazo[1,5-a]pyrimidine-4-carboxylic acid (CAS 924137-97-3)
- L-Glutamic acid γ-(3-carboxy-4-hydroxyanilide) (CAS 74929-17-2)
- 7-Deazaguanosine (CAS 62160-23-0)
- 1-Ethyl-2-isocyano-benzene (CAS 63212-32-8)
- (1-(2-(Thiophen-3-yl)ethyl)cyclohexyl)methanamine (CAS 1342179-84-3)
- 2-Phenylpyridin-3-ol (CAS 3308-02-9)
- (1,3-Dioxoisoindolin-2-yl)methyl 2-((4-methoxyphenyl)thio)acetate (CAS 869714-54-5)
- 1311283-68-7 N'-[1-(4-Chloro-phenyl)-meth-(E)-ylidene]-N-(6-chloro-4-trifluoromethyl-pyridin-2-yl)-N-methyl-hydrazine MFCD19981165 (CAS 1311283-68-7)
- 4-Fluoro-4-methylpiperidine Hydrochloride (CAS 1023305-87-4)
- Apalutamide Impurity 116 (CAS CATO-C4X-2749116)
- 4-[2-(2-Nitrophenoxy)ethyl]piperidinehydrochloride (CAS 1219982-52-1)
- Tert-butyl (R)-3-methyl-4-(6-nitropyridin-3-yl)piperazine-1-carboxylate (CAS 1433989-88-8)
- Insulin Degludec Impurity 2 (CAS CATO-C4X-21572)
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