2,2,2-Trifluoro-1-(pyrrolidin-1-yl)ethanone CAS 6442-87-1
| CAS No. | 6442-87-1 |
| Molecular Formula | C6H8F3NO |
| Molecular Weight | 167.13 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
2,2,2-Trifluoro-1-(pyrrolidin-1-yl)ethanone (CAS 6442-87-1), molecular formula C6H8F3NO and molecular weight 167.13 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2,2,2-Trifluoro-1-(pyrrolidin-1-yl)ethanone (C6H8F3NO) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 2,2,2-Trifluoro-1-(pyrrolidin-1-yl)ethanone under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H8F3NO |
| Molecular Weight | 167.13 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1958 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoro Standards
- 2,2,2-trifluoro-1-(1H-pyrrol-2-yl)ethanone 2,2,2-tris(fluoranyl)-1-(1H-pyrrol-2-yl)ethanone 2557-70-2 A817914 (CAS 2557-70-2)
- (Z)-1,1,1-trifluoro-4-methoxypent-3-en-2-one (CAS 102145-82-4)
- 2,2,2-Trifluoro-1-(tetrahydro-3-furanyl)ethanone (CAS 1339862-66-6)
- 1,1,1-Trifluoro-4-methoxy-,(3e)-3-penten-2-one (CAS 135351-20-1)
- 1,1,1-Trifluoro-3-methylpentane-2,4-dione (CAS 360-82-7)
- 2,2,2-Trifluoro-1-(tetrahydrofuran-2-yl)ethan-1-one (CAS 2090295-28-4)
- 4,4,4-Trifluoro-3-methyl-but-2-enoic acid methyl ester (CAS 671-82-9)
- 2,2,2-trifluoro-1-(1H-pyrazol-4-yl)ethan-1-one (CAS 161957-47-7)
Recommended Standards
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- 6-Formamido-1,2,4-triazine-5-carboxamide (CAS 19359-68-3)
- 4-(3-Methyl-1,2,4-oxadiazol-5-yl)-1,2,5-oxadiazol-3-amine (CAS 893772-68-4)
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Why CATO?
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