1-(4-Fluorophenyl)-2,2-dimethylpropan-1-one CAS 64436-59-5

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Fluorophenyl)-2,2-dimethylpropan-1-one.

1-(4-Fluorophenyl)-2,2-dimethylpropan-1-one (CAS 64436-59-5) is a high-purity analytical reference standard with the molecular formula C11H13FO and a molecular weight of 180.22 g/mol.

Owing to a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, 1-(4-Fluorophenyl)-2,2-dimethylpropan-1-one is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 180.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 1-(4-Fluorophenyl)-2,2-dimethylpropan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

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