2-Chloro-5-(piperidine-1-sulfonyl)pyridine CAS 64614-52-4
| CAS No. | 64614-52-4 |
| Molecular Formula | C10H13ClN2O2S |
| Molecular Weight | 260.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-5-(piperidine-1-sulfonyl)pyridine.
CATO supplies 2-Chloro-5-(piperidine-1-sulfonyl)pyridine (CAS 64614-52-4), a certified reference material (molecular formula C10H13ClN2O2S, MW 260.74 g/mol) for analytical method development and quality control.
The molecular framework of 2-Chloro-5-(piperidine-1-sulfonyl)pyridine (C10H13ClN2O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H13ClN2O2S |
| Molecular Weight | 260.74 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 4-Chloro-2-(5-methylthiophen-2-yl)quinazoline (CAS 1019325-36-0)
- 6-Chloro-N-(cyclobutylmethyl)pyridine-3-sulfonamide (CAS 1095174-72-3)
- 4-(7-chloro-1,3-benzothiazol-2-yl)aniline (CAS 1096285-07-2)
- 2-Chloro-N-cyclopentylpyridine-3-sulfonamide (CAS 1155913-42-0)
- 5-Chloro-3-[(naphthalen-1-yl)methyl]-1,2,4-thiadiazole (CAS 1221342-78-4)
- 6-Chloro-2-(p-tolyl)thiazolo[4,5-b]pyridine (CAS 124522-22-1)
- 4-Chloro-2-methyl-6-phenylthieno[2,3-d]pyrimidine (CAS 125660-99-3)
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Recommended Standards
- 2-Chloro-3-(piperidine-1-sulfonyl)pyridine (CAS 60597-71-9)
- 2-Chloro-5-(pyrrolidine-1-sulfonyl)aniline (CAS 328028-27-9)
- 2-Chloro-2-(thiomethyl)benzophenone (CAS 951887-97-1)
- 3-(Benzo[d]thiazol-2-yl)-4-chloroaniline (CAS 292644-36-1)
- Meester-4,6-Dioxoheptanoicacid (CAS 80480-42-8)
- 1-Benzyl-3-(biphenyl-4-yl)thiourea (CAS 854644-24-9)
- 1,3-Bis(2-(5-bromothiophen-2-yl)ethyl)urea (CAS 2432029-02-0)
- 3-Oxo-3-(thieno[2,3-b]pyridin-2-yl)propanenitrile (CAS 1186405-15-1)
- 12-methoxy-5-thia-1,10,11-triazatricyclo[6.4.0.0²⁶]dodeca-2(6),3,7,11-tetraen-9-one (CAS 2730031-08-8)
- 4-(2-Fluorophenyl)butan-1-amine (CAS 1017226-33-3)
- 1-(2,4-Dichloro-5-isopropoxyphenyl)-2-(methylthio)-1H-imidazole (CAS 338967-17-2)
- 2-(Dimethylamino)-1,3,8-triazaspiro[4.5]Dec-1-en-4-one (CAS 1227465-49-7)
- (R)-tert-Butyl 3-((6-aminopyrazin-2-yl)oxy)piperidine-1-carboxylate (CAS 1417789-26-4)
- GnRH Associated Peptide (GAP) (1-13), human (CAS 100111-07-7)
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