4,4'-((1,4-Phenylenebis(methylene))bis(oxy))dibenzaldehyde CAS 64621-41-6
| CAS No. | 64621-41-6 |
| Molecular Formula | C22H20O4 |
| Molecular Weight | 348.39 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4,4'-((1,4-Phenylenebis(methylene))bis(oxy))dibenzaldehyde.
4,4'-((1,4-Phenylenebis(methylene))bis(oxy))dibenzaldehyde (CAS 64621-41-6), molecular formula C22H20O4 and molecular weight 348.39 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4,4'-((1,4-Phenylenebis(methylene))bis(oxy))dibenzaldehyde (C22H20O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H20O4 |
| Molecular Weight | 348.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
Related Phenylenebis Standards
- 4,4'-(1,4-Phenylenebis(oxy))dibenzoic acid (CAS 13282-09-2)
- 4,4'-(1,2-Phenylenebis(oxy))dibenzoic acid (CAS 74294-25-0)
- 4,4'-(1,3-Phenylenebis(oxy))dibenzoic acid (CAS 77865-43-1)
- 4,4'-(1,3-Phenylenebis(diazene-2,1-diyl))bis(benzene-1,3-diamine) (CAS 1052-38-6)
- 3,3'-(1,4-phenylenebis(azanediyl))bis(5,5-dimethylcyclohex-2-enone) (CAS 78431-57-9)
- 1,1'-(1,3-Phenylenebis(methylene))bis(3-methyl-1H-pyrrole-2,5-dione) (CAS 119462-56-5)
- 1,4-Phenylenebis((4-chlorophenyl)methanone) (CAS 22198-42-1)
- 2,2',2'',2'''-(1,4-Phenylenebis(azanetriyl))tetraacetic acid (CAS 1099-02-1)
Recommended Standards
- 4-(3-(4-Hydroxy-3-methoxyphenyl)propyl)-2,3,5-trimethoxyphenol (CAS 912957-28-9)
- 4,4'-(3,5-Dihydroxyheptane-1,7-diyl)bis(benzene-1,2-diol) (CAS 408324-01-6)
- 4-(2-(4-(Benzyloxy)phenoxy)ethoxy)benzaldehyde (CAS 937601-87-1)
- 4-Benzyl 1-(tert-butyl) (S)-2-formylpiperazine-1,4-dicarboxylate (CAS 442902-97-8)
- 4-Ethoxy-2-fluorobenzoic acid (CAS 1206593-29-4)
- 4,4-Dimethyl-6-oxopiperidine-3-carboxylic acid (CAS 1785490-30-3)
- 3-Ethoxy-N-((3-methyloxetan-3-yl)methyl)propan-1-amine (CAS 1341344-70-4)
- 4-(2,2-Difluoroethoxy)-2-trifluoromethylphenylamine (CAS 1242458-44-1)
- 4-Fluoro-2-methyl-7-nitro-1H-indole (CAS 1360968-05-3)
- Vazegepant Impurity 40 (CAS CATO-C4X-320040)
- Fluo-4 AM (CAS 273221-67-3)
- 7-Benzyl-2-(4-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(1h)-one (CAS 1030123-18-2)
- 4,6-Difluoronicotinonitrile (CAS 1804896-68-1)
- Tetrapeptide-3 (CAS 827306-97-8)
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