2-Methyl-N-(pyridin-3-yl)-4-(pyrrolidin-1-yl)quinazolin-7-amine CAS 646450-86-4
| CAS No. | 646450-86-4 |
| Molecular Formula | C18H19N5 |
| Molecular Weight | 305.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Methyl-N-(pyridin-3-yl)-4-(pyrrolidin-1-yl)quinazolin-7-amine.
2-Methyl-N-(pyridin-3-yl)-4-(pyrrolidin-1-yl)quinazolin-7-amine (CAS 646450-86-4), molecular formula C18H19N5 and molecular weight 305.38 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Methyl-N-(pyridin-3-yl)-4-(pyrrolidin-1-yl)quinazolin-7-amine (C18H19N5) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 305.38 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Methyl-N-(pyridin-3-yl)-4-(pyrrolidin-1-yl)quinazolin-7-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H19N5 |
| Molecular Weight | 305.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Nitrogen Atoms | 5 |
Recommended Standards
- 1-Methyl-4-(5-methyl-4-(3-morpholinopropyl)-4H-1,2,4-triazol-3-yl)-1H-pyrazol-5-amine (CAS 956964-54-8)
- 3-Ethyl-5-[(Z)-2-thienylmethylidene]-2-(4H-1,2,4-triazol-4-ylimino)-1,3-thiazolan-4-one (CAS 478078-09-0)
- 1-(4-Bromo-1-methyl-1h-pyrrol-2-yl)-2,2,2-trichloroethan-1-one (CAS 184643-69-4)
- 3-Methyl-8-(4-methylpiperidin-1-yl)-7-propyl-3,7-dihydro-1H-purine-2,6-dione (CAS 919017-29-1)
- 1-(Piperidin-1-yl)prop-2-en-1-one (CAS 10043-37-5)
- N1-(5-chloropyridin-2-yl)ethane-1,2-diamine (CAS 92992-92-2)
- (3-Bromo-5-chloro-2-methoxyphenyl)methanol (CAS 871339-17-2)
- tert-Butyl 2-methyl-3-{[(pyridin-3-yl)methyl]amino}propanoate (CAS 1221341-68-9)
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- Anthranilic Acid (15N) (CAS 108159-61-1)
- 3-(Aminomethyl)-6-methyl-1,2,5,6,7,8-hexahydro-1,6-naphthyridin-2-one (CAS 933713-78-1)
- Methyl 4-Oxo-1-(2,4,5-trifluorophenyl)cyclohexanecarboxylate (CAS 1385694-46-1)
- Ethyl N-(tert-butoxycarbonyl)-S-(2-(3,4-dichlorophenyl)-2-oxoethyl)cysteinate (CAS 1101164-92-4)
- Tau Peptide (274-288) trifluoroacetate salt (CAS 330456-39-8)
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