N,N-diethyl-2-methyl-6-(trifluoromethyl)nicotinamide CAS 646455-72-3
| CAS No. | 646455-72-3 |
| Molecular Formula | C12H15F3N2O |
| Molecular Weight | 260.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of N,N-diethyl-2-methyl-6-(trifluoromethyl)nicotinamide is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies N,N-diethyl-2-methyl-6-(trifluoromethyl)nicotinamide (CAS 646455-72-3), a certified reference material (molecular formula C12H15F3N2O, MW 260.26 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, N,N-diethyl-2-methyl-6-(trifluoromethyl)nicotinamide is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 260.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures N,N-diethyl-2-methyl-6-(trifluoromethyl)nicotinamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H15F3N2O |
| Molecular Weight | 260.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- N-(5-Amino-2-methoxyphenyl)-4-fluorobenzamide (CAS 926255-98-3)
- N-[3-(2-Amino-4-fluorophenoxy)phenyl]acetamide (CAS 946774-96-5)
- N-(5-amino-2-methoxyphenyl)-3-fluorobenzamide (CAS 926250-50-2)
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- (S)-2-((tert-Butoxycarbonyl)(methyl)amino)-2-(3-iodo-4-methoxyphenyl)acetic acid (CAS 1253795-10-6)
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- 3-[1-(3,4-Difluorobenzoyl)piperidin-4-yl]-4-phenyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775382-66-5)
- Tirzepatide Impurity 20 (CAS CATO-C4X-324020)
Why CATO?
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