N'1-[5-chloro-2-nitro-4-(trifluoromethyl)phenyl]-2,6-dimethoxybenzene-1-carbohydrazide CAS 646498-08-0
| CAS No. | 646498-08-0 |
| Molecular Formula | C16H13ClF3N3O5 |
| Molecular Weight | 419.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 419.74 g/mol gives N'1-[5-chloro-2-nitro-4-(trifluoromethyl)phenyl]-2,6-dimethoxybenzene-1-carbohydrazide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
N'1-[5-chloro-2-nitro-4-(trifluoromethyl)phenyl]-2,6-dimethoxybenzene-1-carbohydrazide (CAS 646498-08-0) is a high-purity analytical reference standard with the molecular formula C16H13ClF3N3O5 and a molecular weight of 419.74 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N'1-[5-chloro-2-nitro-4-(trifluoromethyl)phenyl]-2,6-dimethoxybenzene-1-carbohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 419.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N'1-[5-chloro-2-nitro-4-(trifluoromethyl)phenyl]-2,6-dimethoxybenzene-1-carbohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H13ClF3N3O5 |
| Molecular Weight | 419.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- Ethyl 5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-4,6-dioxo-1H,3aH,4H,5H,6H,6aH-pyrrolo[3,4-c]pyrazole-3-carboxylate (CAS 321522-16-1)
- 1-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}-3-cyanopropan-2-yl 2,6-difluorobenzoate (CAS 338399-93-2)
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- N-(3-chloro-4-(2,6-dinitro-4-(trifluoromethyl)phenoxy)phenyl)acetamide (CAS 338413-17-5)
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- 2-Chloro-5-[(prop-2-en-1-yl)[3-(trifluoromethyl)phenyl]sulfamoyl]benzoic acid (CAS 723332-75-0)
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Recommended Standards
- TERT-BUTYL 2,2,3,3,9,9,10,10-OCTAMETHYL-4,8-DIOXA-3,9-DISILAUNDECAN-6-YLCARBAMATE (CAS 1951440-94-0)
- tert-Butyl 4-(2-(4-bromo-2-chlorophenoxy)ethyl)piperazine-1-carboxylate (CAS 1704074-14-5)
- [4-(2,4-Difluorophenoxy)-3-nitrophenyl]methyl 3-chlorobenzoate (CAS 338960-94-4)
- tert-butyl ((1-((5-bromo-2-chloropyrimidin-4-yl)amino)cyclohexyl)methyl)carbamate (CAS 1374635-87-6)
- 3-(4-Benzyl-2-bromophenoxy)piperidinehydrochloride (CAS 1220017-31-1)
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- 4-Amino-3-methylpicolinic acid (CAS 1782591-26-7)
- Benzyl 3-((2-amino-N-methylacetamido)methyl)pyrrolidine-1-carboxylate (CAS 1353954-95-6)
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- 6-Methoxy-N-(3-(trifluoromethyl)benzyl)-2H-chromene-3-carboxamide (CAS 338760-52-4)
- 118618-61-4 1-Methyl-1H-indole-2-carbonyl chloride DTXSID90486652 (CAS 118618-61-4)
- (Des-Thr7)-Glucagon trifluoroacetate salt (CAS 1802078-28-9)
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