2-Chloro-6-(pyrimidin-2-ylthio)-1H-purine CAS 646509-53-7
| CAS No. | 646509-53-7 |
| Molecular Formula | C9H5ClN6S |
| Molecular Weight | 264.69 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Chloro-6-(pyrimidin-2-ylthio)-1H-purine.
2-Chloro-6-(pyrimidin-2-ylthio)-1H-purine (CAS 646509-53-7), molecular formula C9H5ClN6S and molecular weight 264.69 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 2-Chloro-6-(pyrimidin-2-ylthio)-1H-purine (C9H5ClN6S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H5ClN6S |
| Molecular Weight | 264.69 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
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- 3-(5-(Oxazol-5-yl)furan-2-yl)thiophene-2-carboxylic acid (CAS 2197062-01-2)
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- 2'-O-Methyl Lactose (Mixture of Diastereomers) (CAS 77667-98-2)
- 2-Amino-1-(4-chloro-3-methoxyphenyl)ethan-1-ol (CAS 710654-11-8)
- Bis(4-(quinoxalin-2-yl)phenyl)sulfane (CAS 13107-66-9)
- Semaglutide impurity 34 (CAS CATO-C4X-222634)
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