5-Chloro-3-((4-chlorophenyl)sulfonyl)-2-methyl-1H-indole-6-carbonitrile CAS 646514-54-7
| CAS No. | 646514-54-7 |
| Molecular Formula | C16H10Cl2N2O2S |
| Molecular Weight | 365.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 5-Chloro-3-((4-chlorophenyl)sulfonyl)-2-methyl-1H-indole-6-carbonitrile is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 5-Chloro-3-((4-chlorophenyl)sulfonyl)-2-methyl-1H-indole-6-carbonitrile (CAS 646514-54-7), a certified reference material (molecular formula C16H10Cl2N2O2S, MW 365.23 g/mol) for analytical method development and quality control.
Based on its molecular formula C16H10Cl2N2O2S, 5-Chloro-3-((4-chlorophenyl)sulfonyl)-2-methyl-1H-indole-6-carbonitrile contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 365.23 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-3-((4-chlorophenyl)sulfonyl)-2-methyl-1H-indole-6-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H10Cl2N2O2S |
| Molecular Weight | 365.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-2-(4-(4-chlorostyryl)phenyl)benzofuran (CAS 51358-07-7)
- Ethyl 2-{[6-chloro-2-(4-chlorophenyl)-1H-1,3-benzodiazol-1-yl]oxy}acetate (CAS 338978-87-3)
- N-(5-chloro-2-methoxyphenyl)-4-(4-chloro-3-methylphenyl)thiazol-2-amine (CAS 1023834-21-0)
- 2-Chloro-4-(2-ethylpiperidine-1-carboxamido)benzene-1-sulfonyl chloride (CAS 728864-74-2)
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- 4-Chloro-1-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)butan-1-one (CAS 731815-63-7)
- 4-Chloro-N1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)benzene-1,2-diamine (CAS 341966-48-1)
- 6-Chloro-N1-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)benzene-1,2-diamine (CAS 341966-41-4)
Recommended Standards
- 4-Iodo-1-tosylpiperidine (CAS 289890-80-8)
- 5-Methyl-2-(3-pyridinyl)-1,3-thiazol-4-yl 2,4-dichlorobenzenecarboxylate (CAS 338398-95-1)
- 3-(4-Methoxy-benzyloxy)-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzonitrile (CAS 2377609-88-4)
- 5-Methyl-2-(3-pyridinyl)-1,3-thiazol-4-yl 3,5-dichlorobenzenecarboxylate (CAS 338398-97-3)
- N-(3,4-Dimethoxyphenyl)-6-nitroquinazolin-4-amine (CAS 1120331-48-7)
- 5-methyl-4-sulfanylidene-1H,4H-thieno[2,3-d]pyrimidine-6-carboxylic acid (CAS 1176120-44-7)
- 5-Chloro-4-nitro-1H-imidazole (CAS 57531-38-1)
- 3-(1-Methylpiperazin-4-yl)-4-methylsulfonylaniline (CAS 1000018-41-6)
- Allyl butyl ether (CAS 3739-64-8)
- 2-(Methylthio)-1,5-diphenyl-1H-imidazole (CAS 136802-80-7)
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