4-Methyl-1H-indole-2-carbonyl chloride CAS 64679-00-1
| CAS No. | 64679-00-1 |
| Molecular Formula | C10H8ClNO |
| Molecular Weight | 193.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures 4-Methyl-1H-indole-2-carbonyl chloride under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies 4-Methyl-1H-indole-2-carbonyl chloride (CAS 64679-00-1), a certified reference material (molecular formula C10H8ClNO, MW 193.63 g/mol) for analytical method development and quality control.
The molecular framework of 4-Methyl-1H-indole-2-carbonyl chloride (C10H8ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C10H8ClNO |
| Molecular Weight | 193.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
- 4-chloro-N-methyl-quinazolin-2-amine (CAS 2090582-08-2)
- 5-((1H-imidazol-1-yl)methyl)-2-chloropyridine (CAS 230617-61-5)
- 4-Chloro-N-(prop-2-yn-1-yl)benzamide (CAS 24911-37-3)
- 5-(3-Chloro-4-methylphenyl)oxazole (CAS 1996343-80-6)
- 2-(2-Hydroxybut-3-en-1-yl)isoindoline-1,3-dione (CAS 1855-22-7)
- 2-Methyl-1-((tetrahydro-2h-thiopyran-3-yl)amino)propan-2-ol (CAS 1479542-27-2)
- 1-(2-Methoxy-5-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 1082528-64-0)
- 1-(3-Bromophenyl)butan-2-ol (CAS 1179509-17-1)
- 5-(2-Methoxyphenyl)-1H-1,2,4-triazole-3(2H)-thione (CAS 39631-37-3)
- 1-(2-Methoxybenzyl)-1H-indole-2-carboxylic acid (CAS 883539-01-3)
- 3-Chloroindolizine (CAS 63359-55-7)
- Methyl 5-bromo-2-(methylamino)nicotinate (CAS 1220419-53-3)
- 4-[(2-ethoxyphenyl)formamido]butanoic acid (CAS 54464-18-5)
- Semaglutide impurity 274 (CAS CATO-C4X-2226274)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com