2-(((4-Fluorophenyl)amino)methyl)-4-iodo-6-methoxyphenol CAS 647031-84-3
| CAS No. | 647031-84-3 |
| Molecular Formula | C14H13FINO2 |
| Molecular Weight | 373.16 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-(((4-Fluorophenyl)amino)methyl)-4-iodo-6-methoxyphenol is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-(((4-Fluorophenyl)amino)methyl)-4-iodo-6-methoxyphenol (CAS 647031-84-3), a certified reference material (molecular formula C14H13FINO2, MW 373.16 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution, 2-(((4-Fluorophenyl)amino)methyl)-4-iodo-6-methoxyphenol is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 373.16 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(((4-Fluorophenyl)amino)methyl)-4-iodo-6-methoxyphenol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H13FINO2 |
| Molecular Weight | 373.16 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 1 |
Related Fluorophenyl Standards
- 3-(4-Fluorophenyl)-5-(1-(2-fluorophenyl)-1H-pyrazol-3-yl)benzo[c]isoxazole (CAS 321526-22-1)
- 3-(4-Fluorophenyl)-5-[1-(3-fluorophenyl)-1H-pyrazol-3-yl]-2,1-benzoxazole (CAS 321526-21-0)
- 4-[(5-{[(2-Fluorophenyl)amino]carbonyl}-1,3,4-thiadiazol-2-yl)methoxy]benzoic acid (CAS 1142202-82-1)
- 4-(2-((1-(4-Fluorophenyl)-1H-tetrazol-5-yl)thio)acetamido)benzoic acid (CAS 853750-96-6)
- 2-(4-Fluorophenyl)-2-oxoethyl 2-(((benzyloxy)carbonyl)amino)-2-methylpropanoate (CAS 1261118-01-7)
- (2Z)-2-[(2-Fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-yl 2,6-difluorobenzoate (CAS 860788-17-6)
- N-(3-(4-Fluorophenyl)-5,7-dimethylpyrido[3,4-e][1,2,4]triazin-8-yl)benzamide (CAS 121845-84-9)
- Methyl 2-{[4-(4-fluorophenyl)piperazino]methyl}-3-nitrobenzenecarboxylate (CAS 860784-14-1)
Recommended Standards
- (3-(2,4-Dichloro-5-fluorophenyl)-1-(2,4-difluorophenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-78-4)
- 2-(2,6-Dichloro-4-(trifluoromethyl)phenyl)-4-methylphthalazin-1(2H)-one (CAS 672951-12-1)
- Tributyl(5,6-dihydro-4H-pyran-2-yl)stannane (CAS 109669-45-6)
- 3-Chloro-2-[(4-chlorophenyl)(1H-1,2,4-triazol-3-yl)methyl]-5-(trifluoromethyl)pyridine (CAS 338407-59-3)
- 4-chloro-1-(cyclopropylmethoxy)-2-nitrobenzene (CAS 1369950-81-1)
- 1,1,1,3,3,3-Hexafluoropropan-2-yl propyl carbonate (CAS 1980034-68-1)
- IMIDAZO[1,2-A]PYRAZINE-2-METHANOL (CAS 87597-28-2)
- 1-(Trifluoromethyl)-N-methylcyclopropylamine (CAS 1301818-80-3)
- 2-((2-(2-(2-Methoxyethoxy)ethoxy)ethoxy)methyl)oxirane (CAS 73692-54-3)
- Itraconazole Impurity 82 (CAS CATO-C4X-149782)
- 3,5-Dibromo-4-methyl-1H-pyrazole (CAS 60061-54-3)
- 3,5-Dibromo-2-fluorobenzaldehyde (CAS 477535-40-3)
- (e)-3-(Quinolin-2-yl)prop-2-en-1-ol (CAS 150294-54-5)
- D-Ala21-Tirzepatide (CAS CATO-CPTD788913)
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