3-(Bromomethyl)-1-(2-chloro-6-fluorobenzyl)pyridin-2(1H)-one CAS 647825-28-3

Purity 97%+In StockPharmaceutical Standards
CAS No.647825-28-3
Molecular FormulaC13H10BrClFNO
Molecular Weight330.58 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(Bromomethyl)-1-(2-chloro-6-fluorobenzyl)pyridin-2(1H)-one CAS 647825-28-3 chemical structure

Description

The occurrence of 3-(Bromomethyl)-1-(2-chloro-6-fluorobenzyl)pyridin-2(1H)-one is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies 3-(Bromomethyl)-1-(2-chloro-6-fluorobenzyl)pyridin-2(1H)-one (CAS 647825-28-3), a certified reference material (molecular formula C13H10BrClFNO, MW 330.58 g/mol) for analytical method development and quality control.

Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution, 3-(Bromomethyl)-1-(2-chloro-6-fluorobenzyl)pyridin-2(1H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 330.58 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC13H10BrClFNO
Molecular Weight330.58 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1985
Halogen ContentF/Cl/Br-containing
Nitrogen Atoms1

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