N-benzyl-5-chloro-1,3-dimethyl-1H-pyrazole-4-sulfonamide CAS 647825-52-3
| CAS No. | 647825-52-3 |
| Molecular Formula | C12H14ClN3O2S |
| Molecular Weight | 299.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies N-benzyl-5-chloro-1,3-dimethyl-1H-pyrazole-4-sulfonamide (CAS 647825-52-3), a certified reference material (molecular formula C12H14ClN3O2S, MW 299.78 g/mol) for analytical method development and quality control.
The molecular framework of N-benzyl-5-chloro-1,3-dimethyl-1H-pyrazole-4-sulfonamide (C12H14ClN3O2S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14ClN3O2S |
| Molecular Weight | 299.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- 4-(4-Chlorophenyl)-5-(2,2-dimethoxyethyl)-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 477851-06-2)
- Nerandomilast impurity 14 (CAS CATO-C4X-347314)
- 2-Chloro-N-[3-(1H-imidazol-1-yl)propyl]benzene-1-sulfonamide (CAS 321717-89-9)
- N-(4-chlorophenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1023526-15-9)
- 2-Methyl-1-(methylsulfonyl)propan-2-amine (CAS 409095-78-9)
- (1-Amino-3-(dimethylamino)cyclohexyl)methanol (CAS 1522738-87-9)
- 2-(1-{[(9h-fluoren-9-yl)methoxy]carbonyl}piperidin-4-ylidene)acetic acid (CAS 885274-82-8)
- (4-Heptylphenyl)(isoquinolin-4-yl)methanone (CAS 1187169-78-3)
- 1-(4-Fluorophenyl)heptan-1-one (CAS 1766-85-4)
- 3,4-Dibromo-2,5-dimethoxytetrahydrofuran (CAS 91468-55-2)
- 4-Methyl-2-(tributylstannyl)thiazole (CAS 251635-59-3)
- 4-Aminomethyl-2-bromo-3-cyanobenzenesulfonyl chloride (CAS 1807009-97-7)
- 5-Chloropyrimidin-2(1H)-one hydrochloride (CAS 42748-90-3)
- Semaglutide impurity 62 (CAS CATO-C4X-222662)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com