Piperacillin Impurity 81 CAS 64817-23-8
| CAS No. | 64817-23-8 |
| Molecular Formula | C22H29N5O6S |
| Molecular Weight | 491.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Piperacillin Impurity 81 (CAS 64817-23-8, C22H29N5O6S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Piperacillin Impurity 81 (C22H29N5O6S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H29N5O6S |
| Molecular Weight | 491.56 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Piperacillin Standards
- Piperacillin EP Impurity C (CAS 2649505-15-5)
- Piperacillin Impurity 44 (CAS 90686-52-5)
- Piperacillin EP Impurity K (CAS 2734474-72-5)
- Piperacillin Monohydrate EP Impurity N (CAS CATO-C4X-173219)
- Piperacillin Impurity 31 (CAS CATO-C4X-173231)
- Piperacillin Impurity 38 (CAS CATO-C4X-173238)
- Piperacillin Impurity 57 (CAS CATO-C4X-173257)
- Piperacillin (CAS CATO-C4X-173245)
Recommended Standards
- 1-(4-tert-Butylbenzenesulfonyl)-4-{5-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-yl}piperidine (CAS 1025724-85-9)
- Sulfo-DMAC-SPP (CAS 663599-11-9)
- Methyl 4-Tosyl Mycophenoate-6-methyl-d (CAS 1185240-84-9)
- N-(3,5-Dimethoxyphenyl)-2-((4-(4-ethoxyphenyl)-5-(pyridin-3-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 477330-20-4)
- Treprostinil Impurity 13 (CAS CATO-C4X-211613)
- Itraconazole Impurity 83 (CAS CATO-C4X-149783)
- Apalutamide Impurity 17 (CAS CATO-C4X-274917)
- 2-mercaptopyrimidine (CAS 1450-85-7)
- Bethoxazin (CAS 163269-30-5)
- Tert-butyl (1-(4-methoxyphenyl)cyclopropyl)carbamate (CAS 197655-12-2)
- 5-Fluoro-2-(1H-pyrazol-4-yl)pyridine (CAS 1381971-92-1)
- 2-(2-Amino-6-(difluoromethyl)-3-(trifluoromethyl)pyridin-4-yl)acetonitrile (CAS 1805381-46-7)
- (4,5-Dimethyl-6-oxopyrimidin-1(6H)-yl)acetic acid (CAS 1216060-16-0)
- Semaglutide impurity 63 (CAS CATO-C4X-222663)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com