6-Bromo-2-chloro-4-phenyl-quinazoline CAS 64820-57-1
| CAS No. | 64820-57-1 |
| Molecular Formula | C14H8BrClN2 |
| Molecular Weight | 319.58 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 6-Bromo-2-chloro-4-phenyl-quinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
6-Bromo-2-chloro-4-phenyl-quinazoline (CAS 64820-57-1), molecular formula C14H8BrClN2 and molecular weight 319.58 g/mol, is a CATO reference standard with documented purity and traceability.
6-Bromo-2-chloro-4-phenyl-quinazoline (C14H8BrClN2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8BrClN2 |
| Molecular Weight | 319.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1975 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- Methyl 5-bromo-4-(chlorosulfonyl)thiophene-2-carboxylate (CAS 1087792-15-1)
- Methyl 4-Bromo-5-(chlorosulfonyl)thiophene-2-carboxylate (CAS 1306606-67-6)
- 2-(4-Bromo-phenyl)-4-chloro-quinazoline (CAS 83800-98-0)
- 6-Bromo-4-chloro-2-phenylquinazoline (CAS 412923-42-3)
- 7-Bromo-4-chloro-2-phenylquinazoline (CAS 887592-38-3)
- n-(4-Bromo-2-chlorophenyl)morpholine-4-carboxamide (CAS 895643-84-2)
- N-{2-[(4-bromo-2-methylphenyl)amino]-2-oxoethyl}-2-chloroacetamide (CAS 756859-07-1)
- 1-Bromo-8-chloro-6-fluoro-3-(methoxymethoxy)naphthalene (CAS 2852769-94-7)
Recommended Standards
- (E)-Ethyl 2-(1-bromoethylidene)-6-chloro-1-vinyl-1,2-dihydropyrimidine-5-carboxylate 1785773-35-4 (CAS 1785773-35-4)
- n-(2-((2-Bromophenyl)amino)-2-oxoethyl)-2-chloro-N-methylacetamide (CAS 796084-52-1)
- 1000576-15-7 Isopropyl 2-[2-(4-bromophenyl)hydrazono]-2-chloroacetate MFCD09877871 (CAS 1000576-15-7)
- Resmetirom impurity 63 (CAS CATO-C4X-291263)
- (S,S)-6-BENZYL-OCTAHYDRO-PYRROLO[3,4-B]PYRIDINE 2HCL (CAS 1059609-67-4)
- 3-(Allylamino)tetrahydrothiophene 1,1-dioxide hydrochloride (CAS 5553-32-2)
- methyl 4-amino-6-methylpyrimidine-2-carboxylate (CAS 1520279-43-9)
- 5-Bromo-2-tert-butylaniline (CAS 857595-32-5)
- rel-Methyl (2R,4R)-4-(5-isopropyl-2-methylphenoxy)-2-pyrrolidinecarboxylate (CAS 1217791-17-7)
- Ethyl 2-(2-(4-phenylpiperazin-1-yl)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 833439-05-7)
- Methyl 2-ethyl-3-oxohexanoate (CAS 68039-27-0)
- 3,3-difluoroazepane;hydrochloride (CAS 1228231-35-3)
- 4,5-Dichloronicotinic acid (CAS 473837-10-4)
- Semaglutide Impurity 146 (CAS 2645421-68-5)
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