N'3-[6-methyl-4-(trifluoromethyl)-2-pyridyl]-5-chloro-1-methyl-1H-pyrazole-3-carbohydrazide CAS 648408-74-6
| CAS No. | 648408-74-6 |
| Molecular Formula | C12H11ClF3N5O |
| Molecular Weight | 333.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies N'3-[6-methyl-4-(trifluoromethyl)-2-pyridyl]-5-chloro-1-methyl-1H-pyrazole-3-carbohydrazide (CAS 648408-74-6), a certified reference material (molecular formula C12H11ClF3N5O, MW 333.70 g/mol) for analytical method development and quality control.
N'3-[6-methyl-4-(trifluoromethyl)-2-pyridyl]-5-chloro-1-methyl-1H-pyrazole-3-carbohydrazide (C12H11ClF3N5O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H11ClF3N5O |
| Molecular Weight | 333.70 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 5 |
Recommended Standards
- (2Z)-3-{2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methylhydrazin-1-yl}-2-cyanobut-2-enamide (CAS 303153-04-0)
- N-Nitroso N-desmethylcinolazepam (CAS CATO-C3D-26160)
- Elatol (CAS 55303-97-4)
- 3-(4-Chlorophenylsulfanyl)-5-trifluoromethylpyridine-2-carboxylic acid (CAS 773871-64-0)
- 2-(((5-Chloro-2-methoxyphenyl)amino)methyl)isoindoline-1,3-dione (CAS 859299-43-7)
- 5-(chloromethyl)-1-ethyl-1H-1,2,3-triazole hydrochloride (CAS 1909317-30-1)
- 3,4-Dichloro-N-(3-fluoro-4-(4-(methylsulfonyl)piperazin-1-yl)phenyl)benzamide (CAS 478260-26-3)
- Tert-butyl (1-(pyrrolidine-1-carbonyl)piperidin-4-yl)carbamate (CAS 899806-31-6)
- 1-(2-Bromoethoxy)-3-methoxybenzene (CAS 3245-45-2)
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- 2-Chloro-3-methyl-4-nitropyridine 1-oxide (CAS 60323-95-7)
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